Interaction between adolescent sleep rhythms and gender in an obese population.

Background: The obesity rate of adolescents is gradually increasing, which seriously affects their mental health, and sleep plays an important role in adolescent obesity.

Aim: To investigate the relationship between sleep rhythm and obesity among adolescents and further explores the interactive effect of sleep rhythm and gender on adolescent obesity, providing a theoretical basis for developing interventions for adolescent obesity.

Methods: Research data source Tianjin Mental Health Promotion Program for Students.

[Retracted] MicroRNA‑378 regulates cell proliferation and migration by repressing RNF31 in pituitary adenoma.

[This retracts the article DOI: 10.3892/ol.2017.

[Research progress on natural products of fungi of Diaporthe sp.].

Diaporthe sp. fungi is one of the important sources of active natural products. Polyketides, alkaloids, terpenes, anthraquinones and other types of novel metabolic products are found from this genus, and many of them have significant anti-tumor, antibacterial, anti-hyperlipidemia, inhibition of pulmonary fibrosis, antioxidant and other biological activities.

Effects of different drying methods on the chemical constituents of Lilium lancifolium Thunb. based on UHPLC-MS analysis and antidepressant activity of the main chemical component regaloside A.

The Lilium lancifolium Thunb. is a herb with multiple functions in both medicine and food in China, and its extracts have shown antidepressant effects. In this study, fresh bulbs of Lilium lancifolium Thunb.

Finite Element Analysis of Insertion Angle of Absorbable Screws for the Fixation of Radial Head Fractures.

Objective: To investigate the biomechanical effects of different insertion angles of absorbable screws for the fixation of radial head fractures.

Methods: The finite element models used to simulate the fractures were created based on CT scans. Two absorbable screws were used to fix and maintain the stability of the fracture, and the angles between the screws were set to 0°, 15°, 30°, 45°, 60°, 75°, and 90°.

Automated microfluidic chip system for radiosynthesis of PET imaging probes.

Positron emission tomography (PET) is a powerful non-invasive molecular imaging technique for the early detection, characterization, and "real-time" monitoring of disease, and for investigating the efficacy of drugs (Phelps, 2000; Ametamey et al., 2008). The development of molecular probes bearing short-lived positron-emitting radionuclides, such as F (half-life 110 min) or C (half-life 20 min), is crucial for PET imaging to collect in vivo metabolic information in a time-efficient manner (Deng et al.

MiR-148a inhibits the proliferation and migration of glioblastoma by targeting ITGA9.

Glioblastoma is a common malignant primary intracranial tumor characterized by rapid invasive growth and a high recurrence rate after surgery. MicroRNAs (miRNAs) are involved in cell proliferation, differentiation, and apoptosis, and abnormal miRNA expression is associated with the occurrence and progression of various tumors, including glioblastomas. The aim of this study was to determine the levels of miR-148a and integrin subunit alpha 9 (ITGA9) in glioblastoma tissues and cells and their involvement in cancer cell proliferation and migration.

MicroRNA-378 regulates cell proliferation and migration by repressing RNF31 in pituitary adenoma.

MicroRNA-378 (miR-378) is dysregulated in multiple malignancies and is associated with tumor progression. However, the expression and mechanism of miR-378 in pituitary adenoma (PA) remains to be elucidated. In the present study, the role and mechanism of miR-378 in PA tumorigenesis and development was investigated.

MicroRNA-197 inhibits cell proliferation by targeting GAB2 in glioblastoma.

Glioblastoma is the most common type of primary brain tumor in adults, and is usually fatal in a short duration. Acquiring a better understanding of the pathogenic mechanisms of glioblastoma is essential to the design of effective therapeutic strategies. Grb2-associated binding protein 2 (GAB2) is a member of the daughter of sevenless/Gab family of scaffolding adapters, and has been reported to be important in the development and progression of human cancer.

[Study on Chemical Constituents from Ethyl Acetate Extraction of Sanicula lamelligera].

Objective: To study the chemical constituents from ethyl acetate extraction of Sanicula lamelligera.

Methods: Compounds were isolated and purified by silica gel and Sephadex LH-20 column chromatographic method, and their structures were identified by using spectroscopic analysis.

Results: Nine compounds were isolated and identified as angelicin (I), isoferulaldehyde (II), 12- hydroxybakuchiol (III), 22-angeloyl-R1-barrigenol (IV), 5,6,7,8,4'-pentamethoxyflavone (V),3,5,6,7,8,3',4'-heptamethoxyflavone (VI), isobavachin (VII), isoliquiritigenin (VIII) and furano (2",3",7,6) 4'-hydroxyflavanone (IX).

Correlation between CYP4F2 gene rs2108622 polymorphism and susceptibility to ischemic stroke.

Objective: To conduct a meta-analysis for the correlation between cytochrome P450 4F2 (CYP4F2) rs2108622 (V433M) gene polymorphism and ischemic stroke.

Methods: We retrieved the case-control studies on the correlation between CYP4F2 V433M polymorphism and ischemic stroke included in domestic and international databases before January 2015 and selected the best genetic model, using RevMan 5.2 software for meta-analysis.

Retrospective Analysis of Cushing's Disease with or without Hyperprolactinemia.

Objective. We compared the characteristics of patients with Cushing's disease alone with those of patients with Cushing's disease and hyperprolactinemia. Methods.

Transsphenoidal pseudocapsule-based extracapsular resection for pituitary adenomas.

Background: In the past several years, increasing attention has been paid to the utility of a pseudocapsule in transphenoidal surgery for pituitary adenomas. However, prior studies focused more on the histological structure of the pseudocapsule and surgical technique. The objective of this study was to evaluate the overall therapeutic effectiveness of transsphenoidal pseudocapsule-based extracapsular resection for pituitary adenomas.

[A study on image processing of digital radiography and measure of material micro-density directly].

Due to the high influents of the device itself and the surrounding environment, the background brightness of the digital radiography image is uniform and the image shows big noise. Therefore, in order to identify digital radiography images precisely, a further image processing is necessary. In this study, adaptive filtering, histogram equalization techniques and difference image methods were used for image processing and the results show that these techniques were useful to denoise, to intensify brightness and to rectify the background.

[Diagnosis and treatment of chronic expanding intracerebral hematoma].

Objective: To explore the diagnosis, therapeutic strategy, and pathogenetic mechanism of chronic expanding intracerebral hematoma (CEICH).

Methods: The clinical presentation, radiological characteristics, d pathology, and treatment of 22 cases of CEICH, 15 males and 7 females, aged 29. 3, all treated with craniotomy and removal of the wall of the capsule and hematoma, were analyzed retrospectively.

[Microsurgical treatment of proximal anterior cerebral artery aneurysms].

Objective: To explore clinic characteristics of proximal anterior cerebral artery aneurysms and analyzed operative techniques.

Methods: A review was performed of a total of 362 patients whose aneurysms were surgically treated from June 1995 to December 2003, the morbidity of A(1) aneurysms was 2.2%.

A high-throughput continuous sample introduction interface for microfluidic chip-based capillary electrophoresis systems.

The development of efficient sample introduction and pretreatment systems for microfluidic chip-based analytical systems is important for their application to real-life samples. In this work, world-to-chip interfacing was achieved by a novel flow-through sampling reservoir featuring a guided overflow design. The flow-through reservoir was fabricated on a 30 x 60 x 3 mm planar glass chip of crossed-channel design used for capillary electrophoresis separations.