Publications by authors named "Guang-hua Shi"

Pericellular matrix (PCM) is a narrow tissue region surrounding chondrocytes, which "chondron" with its enclosed cells. A number of studies suggested that PCM is rich in proteoglycans, collagen and fibronectin, and plays an important role in regulating microenvironment of chondrocytes. Direct measures of PCM properties through micropipette aspiration technique showed that PCM was different from mechanical property of chondrocytes and nature extracellular matrix.

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Osteoporosis vertebral compression fractures seriously affect the life and health of the elderly,indicating the elderly life health begin to decline. Therefore, aggressive treatment is particularly important. Traditional surgical method,such as laminectomy and internal fixation has large trauma,more blood loss and high failure rate.

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Objective: To discuss the clinical effects of percutaneous kyphoplasty (PKP) for acute and chronic osteoporotic vertebral compression fractures (OVCF).

Methods: From June 2006 to October 2011,42 senior patients with OVCF were treated with PKP. There were 5 males and 37 females,ranging in age from 60 to 86 years old with an average of (73.

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Objective: To screen out the HAb18G/CD147 binding peptides and find out an antagonist against hepatoma invasion.

Methods: HAb18G/CD147 was purified by affinity chromatographic method and the antigen binding peptides acquired by bio-panning a phage-displayed 12-peptide library. After obtaining the sequence of the selected phage-displayed peptides, all the 9 peptides were synthesized by solid-phase method and identified by mass spectrograph.

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