Publications by authors named "Guang-dong Han"
[Studies on the immuno-protection of ROP2 nuclei acid vaccine in Toxoplasma gondii infection].
Zhongguo Ji Sheng Chong Xue Yu Ji Sheng Chong Bing Za Zhi
October 2006
Article Synopsis
- The study aimed to evaluate the effectiveness of the ROP2 nucleic acid vaccine in protecting mice from Toxoplasma gondii infection by examining immune responses.
- Forty-two BALB/c mice were divided into three groups, with one group receiving the ROP2 vaccine while the others received control injections; after three immunizations, immune responses were measured and the mice were exposed to the parasite.
- Results showed the vaccine triggered a strong immune response, significantly improving survival rates and delaying death in vaccinated mice compared to controls, highlighting its potential as an immunoprotective agent.
[Cloning and identification of ROP2 gene of Toxoplasma gondii].
Zhongguo Ji Sheng Chong Xue Yu Ji Sheng Chong Bing Za Zhi
June 2006
Objective: To amplify ROP2 from the genomic DNA of Toxoplasma gondii RH strain and construct eukaryotic expression plasmid pc-DNA3-ROP2.
Methods: Tachyzoites of T. gondii RH strain were collected and depurated to obtain genome.