Publications by authors named "Guang-Zhi Shi"

Objectives: The purpose of this study was to evaluate the predictive value of the cough peak flow (CPF) for successful extubation in postcraniotomy critically ill patients.

Design: This was a single-centre prospective diagnostic study.

Setting: The study was conducted in three intensive care units (ICUs) of a teaching hospital.

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  • * A systematic review and meta-analysis were conducted, including 39 studies with over 9,600 patients, using quality assessments and various statistical measures to analyze data from multiple medical databases.
  • * Findings indicate that PSD is a significant independent predictor of increased mortality and poor neurological function, alongside other negative outcomes like prolonged hospital stays and diminished quality of life post-discharge.
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  • Delirium is a major health issue for acute stroke patients, and the study aims to summarize existing evidence through a meta-analysis of its occurrence and risk factors.
  • A thorough search of databases led to the inclusion of 49 studies involving 12,383 patients, revealing that 24.4% of post-stroke patients experienced delirium, with specific subtypes identified.
  • Key risk factors for delirium included older age, low education, smoking, alcohol use, heart issues, and pre-existing cognitive impairments, indicating the need for targeted prevention and intervention strategies.
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Objectives: To define the core competencies essential for specialist training in neurocritical care in China.

Design: Modified Delphi method and nominal group (NG) technique.

Setting: National.

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Background: Post-operative volume of subdural fluid is considered to correlate with recurrence in chronic subdural haematoma (CSDH). Information on the applications of computer-assisted volumetric analysis in patients with CSDHs is lacking.

Objective: To investigate the relationship between haematoma recurrence and longitudinal changes in subdural fluid volume using CT volumetric analysis.

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Background: It has been confirmed that the concentration of cefepime in cerebrospinal fluid (CSF) could reach the 10% of its concentration in plasma, exceeding the inhibitory concentration to 90% of organisms (MIC(90)) for common bacteria. However, the blood-brain barrier (BBB) penetration ability of cefepime is still unclear. The aim of this study was to measure the CSF concentration of cefepime in patients after neurosurgical operations, and to determine the penetration of the drug through an incomplete BBB.

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