Opposite effects of sevoflurane at high and low concentration on the airway inflammation in juvenile asthma rats: A TMT-based proteomics analysis study.

Background: The incidence of sevoflurane-related adverse respiratory events in children with asthma is notably high. During different phases of sevoflurane anesthesia, asthmatic children's airways are exposed to varying concentrations of the anesthetic. However, the specific effects of different concentrations of sevoflurane on the developing airways with asthmatic hyperreactivity have not been systematically studied.

Applications of the ultrasound-guided nerve block technique for nonanalgesic effects.

The nerve block technique guided by ultrasound has been able to accurately block tiny nerves throughout the body in recent years. It has been increasingly used to treat multisystem diseases or analgesia in surgical patients, but the latter accounted for the vast majority of cases. The nonanalgesic effect of nerve blocks is also in wide demand.

The expanded effects of sevoflurane on the nervous system: the harmful effect of residual concentration of sevoflurane on the respiratory system through neurogenic inflammation.

Background: Neurogenic inflammation caused by sevoflurane may not only limite to the nervous system, but also expand to the respiratory system. The purpose of this study was to investigate the expression changes of transient receptor potential vanilloid 1 (TRPV1), neurokinin A (NKA), neurokinin B (NKB), calcitonin gene related peptide (CGRP) and substance P (SP) in 14, 21 and 42-day-old rats after inhaling 0.4% sevoflurane, in order to evaluate whether the residual sevoflurane be harmful to the respiratory system through neurogenic inflammation.