Publications by authors named "Guang-Qiang Ma"

Article Synopsis
  • Drug resistance caused by bacterial biofilms makes antibiotics less effective, prompting research to find ways to eliminate these biofilms.
  • Recent studies have shown that biofilm formation and resistance are complex processes influenced by various factors.
  • This paper reviews how biofilms form and explores the use of natural drugs to disrupt them, providing useful insights for future research.
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In this work, an unmodified homogeneous electrochemical sensor based on electrochemical bonding and catalytic hairpin assembly (CHA) was first constructed for the high sensitivity detection of Hg. Herein, tetraferrocene, a synthesized compound, was used as a signal marker that modified both ends of the hairpin probe to amplify the electrochemical signal. The interaction of T-Hg-T could induce the catalytic self-assembly of hairpins by means of auxiliary DNA.

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Three new neoflavonoids, named (1,8,9)-1,5-dihydroxy-4,12-dimethoxy-8-vinyl-tricyclo[7.3.1.

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A new neoflavonoid, named (+)-3'-hydroxy-4',2,4,5-tetramethoxydalbergiquinol (), and a new benzofuran, named (2,3)-5-hydroxy-6-methoxy-3-methyl-2-(4'-hydroxyphenyl)-2,3dihydrobenzofuran , together with two known neoflavonoids, were isolated from the heartwood of Their structures were elucidated by a combination of spectroscopic methods and comparison with the literature. Compounds were evaluated for inhibitory activity against ATCC 25923, ATCC 6538, CMCC 50041 and ATCC 289065, which all exhibited inactive or weak activity.

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Ethnopharmacological Relevance: Scutellaria-coptis herb couple (SC) is one of the well-known herb couples in many traditional Chinese compound formulas used for the treatment of diabetes mellitus (DM), which has been used to treat DM for thousands of years in China.

Aim Of The Study: Few studies have confirmed in detail the anti-diabetic activities of SC in vivo and in vitro. The present investigations aimed to evaluate the anti-diabetic activity of SC in type 2 diabetic KK-Ay mice and in RAW264.

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This research was undertaken in order to characterize the chemical compositions and evaluate the antioxidant activities of essential oils obtained from different parts of the Origanum vulgare L. It is a medicinal plant used in traditional Chinese medicine for the treatment of heat stroke, fever, vomiting, acute gastroenteritis, and respiratory disorders. The chemical compositions of the three essential oils from different parts of the oregano (leaves-flowers, stems, and roots) were identified by gas chromatography-mass spectrometry (GC-MS).

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A new alkaloid, named 2-methoxy-4-(2-(2-pyridine)-ethyl) phenol (1), together with two known compounds, was isolated from Zingiberis rhizoma. Their structures were elucidated on the basis of 1D and 2D NMR spectra and MS spectra. Compound 1 exhibited substantial bioactivity against Canidia albicans ATCC 10231 with a minimum inhibitory concentration of 1.

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