Publications by authors named "Guang-Nan Zhuang"
Article Synopsis
- Microarrays enable large-scale biological analysis through their ability to perform massive and parallel testing.
- Researchers applied rolling circle amplification (RCA) on oligonucleotide-decorated polymer brushes attached to porous silicon to enhance the sensitivity of nucleic acid detection while maintaining the ability to detect multiple targets at once.
- This innovative method achieved a detection limit of 0.1 nM and a dynamic range of 0.1-100 nM, demonstrating its potential for multiplexing DNA detection on a single chip.
