Chemical cross-linking approach for prolonging diclofenac sodium release from pectin-based delivery system.

To overcome the instability of pectin-Ca gels based oral colon-specific drug delivery system (OCDDS) in the upper gastrointestinal tract, the chemical cross-linked pectin carriers were prepared by adding succinic anhydride and glutaric dialdehyde as the cross-linking reagents. The diclofenac sodium was employed as the water-soluble drug model to calculate the controlled release properties. The encapsulation efficiency and loading efficiency were measured and the sample PG1 shows the best efficiency of 78.

Pectin microgel particles as high adsorption rate material for methylene blue: Performance, equilibrium, kinetic, mechanism and regeneration studies.

The pectin gel has been proved to be an effective material for methylene blue (MB) removal, but it presented low adsorption rate. To get over the vice, the pectin microgel particles (PMP) was prepared. No matter high or low initial MB concentration, the PMP presented high adsorption rate with equilibrium time of 20min.

Combined effects of independent variables on yield and protein content of pectin extracted from sugar beet pulp by citric acid.

The extraction of pectin from sugar beet pulp by citric acid was carried out under different conditions using Box-Behnken design for four independent variables (pH, temperature, time and liquid to solid ratio). The yield of sugar beet pulp pectin ranged from 6.3% to 23.