A pharynx-to-brain axis controls pharyngeal inflammation-induced anxiety.

Anxiety is a remarkably common condition among patients with pharyngitis, but the relationship between these disorders has received little research attention, and the underlying neural mechanisms remain unknown. Here, we show that the densely innervated pharynx transmits signals induced by pharyngeal inflammation to glossopharyngeal and vagal sensory neurons of the nodose/jugular/petrosal (NJP) superganglia in mice. Specifically, the NJP superganglia project to norepinephrinergic neurons in the nucleus of the solitary tract (NTS).

[Clinical analysis of vocal fold firbrous mass].

Objectives: To explore the character of laryngoscopy finding, voice, and therapy of vocal fold fibrous mass.

Methods: Clinical data, morphology, voice character, surgery and pathology of 15 cases with vocal fold fibrous mass were analyzed.

Results: The morbidity of vocal fold fibrous mass might be related to overuse of voice and laryngopharyngeal reflex.

[Prevention of anterior glottic stenosis after CO2 laser cordectomy with chitosan].

Objective: To observe the effect of immediate topical application of chitosan on preventing anterior glottic stenosis (AGS) after microsurgical resection of both vocal fold with CO2 laser, including the anterior commissure, in a canine model.

Methods: Sixteen canine larynges were injured by microresecting procedure of both vocal folds with CO2 laser. The dogs were randomly divided into two groups, chitosan group and control group.

Peri- and post-operative complications after carbon dioxide laser surgery of the larynx.

Objective: To analyze the complications of transoral laser surgery (TLS) for larynx tumors in a single center institution, and to highlight its possible risks.

Methods: This is a retrospective study of the peri- and post-operative complications of 500 patients who underwent TLS from November 2001 to July 2008 in the Department of Otolaryngology, Head and Neck Surgery, Anhui Provincial Hospital, Anhui Medical University, Hefei, China.

Results: The total rate of complications was 10.

[Transoral endoscopic CO2 laser surgery for hypopharynx in experimental animals].

Objective: To explore the substantial resection limits of CO2 laser surgery for hypopharynx and the course of wound healing in animals, for the purpose of evaluating the clinic usefulness of transoral CO2 laser surgery in the treatment of selected hypopharyngeal carcinomas.

Methods: Twenty-three dogs were randomly assigned to two groups. Group one (11 dogs) received left piriform sinus resection, group two (12 dogs) received the resection of posterior wall of the hypopharynx.