Publications by authors named "Guang-Lin Liu"
Article Synopsis
- A carotid-cavernous fistula (CCF) is an abnormal connection between the internal carotid artery and the cavernous sinus, often resulting from trauma or neuroendovascular procedures, including mechanical thrombectomy (MT) for stroke.
- The case study details a 60-year-old woman who suffered from a stroke and developed a CCF after undergoing MT; she later improved after undergoing embolization for the CCF.
- Understanding the anatomical variations, like the tortuosity of the internal carotid artery, is crucial for predicting and preventing complications like CCF in patients undergoing MT.
Nearly all clinical trials that have attempted to develop effective strategies against ischemic stroke have failed, excluding those for thrombolysis, and most of these trials focused only on preventing neuronal loss. However, astrocytes have gradually become a target for neuroprotection in stroke. In previous studies, we showed that the newly identified molecular N-myc downstream-regulated gene 2 (Ndrg2) is specifically expressed in astrocytes in the brain and involved in some neurodegenerative diseases.
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- Magnolia sieboldii is a deciduous tree from China that has a unique deep dormancy, and researchers analyzed changes in its seed protein at various stratification stages to understand its germination better.
- The study found 80 different proteins with varying levels of abundance during seed stratification, with specific proteins like ADP-glucose pyrophosphorylase degrading during germination, indicating their role in energy metabolism and embryo development.
- The analysis revealed that starch granules diminished over time, providing critical nutrients for germination, and identified four storage proteins that decreased in quantity, contributing to seed readiness for growth.
Peroxisome proliferator-activated receptorĀ Ī³ (PPARĪ³) is a ligand-activated nuclear receptor which has been implicated in carcinogenesis and angiogenesis in a wide range of cancers, including pancreatic carcinoma (PC). We aimed to characterize the prognosis and potential therapeutic implications of PPARĪ³ in PC. Real-time RT-PCR and western blotting were used to quantify PPARĪ³ expression in immortalized pancreatic epithelial cells, PC cell lines and freshly isolated matched tumor and non-tumor tissues.
View Article and Find Full Text PDF4-Nitro-N^2^-(pyridin-4-ylmethylidene)benzene-1,2-diamine.
Acta Crystallogr Sect E Struct Rep Online
September 2013
In the title compound, C12H10N4O2, the dihedral angle between the aromatic rings is 43.18ā (16)Ā°. The nitro group is rotated from its attached ring by 7.
View Article and Find Full Text PDF4-Meth-oxy-3-(meth-oxy-meth-yl)benzalde-hyde.
Acta Crystallogr Sect E Struct Rep Online
January 2013
In the title compound, C10H12O3, the dihedral angle between the benzene ring and the meth-oxy-methyl side chain is 9.7ā (2)Ā°. The O atom of the aldehyde group and the C atom of the meth-oxy group deviate from the plane of the ring by 0.
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- Breast cancer is a major cause of cancer-related deaths globally, and this study focused on the role of centromere protein H (CENP-H) as a potential biomarker.
- The researchers found that CENP-H was expressed at higher levels in breast cancer cells compared to normal cells, with high expression detected in 43.6% of analyzed breast cancer samples.
- Statistical analyses indicated that high CENP-H levels correlated with worse clinical outcomes, including shorter overall survival, making it an important independent indicator for breast cancer prognosis.