Synopsis of recent research by authors named "Guang-Hao Zhu"
- Guang-Hao Zhu's recent research focuses on the discovery and characterization of naturally occurring compounds that inhibit key gut microbial enzymes and human digestive enzymes, which play significant roles in metabolic diseases like colorectal cancer and obesity.
- His studies highlight the potential of botanical extracts, such as those from Platycladi cacumen and Rhodiola crenulata, as broad-spectrum inhibitors of gut microbial β-glucuronidases and bile salt hydrolases, aiming to mitigate drug-induced gastrointestinal toxicity and improve medication efficacy.
- Additionally, Zhu is exploring the development of selective inhibitors for human pancreatic lipase and the identification of covalent inhibitors against SARS-CoV-2 proteases, leveraging medicinal plants and synthetic compounds to address pressing health challenges like food allergies and viral infections.
