The association between interleukin-19 concentration and diabetic nephropathy.

Background: Interleukin-19 (IL-19) is a newly discovered cytokine belonging to the Interleukin-10(IL-10) family. IL-19 have indispensable functions in many inflammatory processes and also can induce the angiogenic potential of endothelial cells. The purpose of present study was to investigate the relation of serum interleukin-19 (IL-19) levels with diabetic nephropathy (DN).

Association between interleukin-19 and angiopoietin-2 with vascular complications in type 2 diabetes.

Aims/introduction: The aim of the present study was to investigate the role of interleukin-19 (IL-19) in angiogenesis of type 2 diabetes mellitus with complications, and to assess the relationship of serum IL-19 and angiopoietin-2 (Ang-2) in type 2 diabetes mellitus.

Materials And Methods: The group studied comprised of 240 patients with type 2 diabetes mellitus (132 men and 108 women), and included macrovascular complications, microvascular complications and type 2 diabetes mellitus without vascular complications. The control group consisted of 50 healthy blood donors.

Interleukin-19 and angiopoietin-2 can enhance angiogenesis of diabetic complications.

This study was to investigate the role of interleukin-19 (IL-19) and angiopoietin-2 (Ang-2) in angiogenesis of type 2 diabetes (T2DM). In 240 patients with T2DM, IL-19 and Ang-2 levels were higher, IL-19 was positively correlated with Ang-2. IL-19 and Ang-2 might be involved in angiogenesis of T2DM complications.