Aortic endograft infection after thoracic endovascular aortic repair: two case reports and literature review.

With the maturity of thoracic endovascular aortic repair (TEVAR) technology and its increasing application in clinical practice, complications and long-term management after TEVAR have become issues of concern. Here, we report two cases of TEVAR for thoracic aortic dissection. One patient developed recurrent fever 6 years after TEVAR and underwent multiple courses of antibiotic therapy with a poor response.

Effect of Fluorine Contamination from Multilayer Dielectric Grating Fabrication on Picosecond-Laser-Induced Damage Resistance.

Contamination introduced by multilayer dielectric grating (MLDG) fabrication increases the risk of laser-induced damage when exposed to intense laser fields, consequently reducing the laser-induced damage resistance of MLDGs in picosecond-petawatt laser systems. While considerable efforts have focused on cleaning methods to minimize contamination, studies on optimizing the etching process remain limited. In this study, two different beam-current etching protocols were employed in fabricating MLDGs and thin films to comprehensively evaluate the adverse effects of subsurface defects introduced by the etching process.

Carnosic Acid Directly Targets STING C-Terminal Tail to Improve STING-Mediated Inflammatory Diseases.

cGAS (cyclic GMP-AMP synthase)-STING (stimulator of interferon genes) signaling plays a vital role in innate immunity, while its deregulation may lead to a wide variety of autoinflammatory and autoimmune diseases. It is essential to identify specifically effective lead compounds to inhibit the signaling. Herein, it is shown that carnosic acid (CA), an active ingredient of medicinal plant Rosmarinus officinalis L.

Detection of DNA in Deer Keds: Massachusetts, USA.

Deer keds ( spp. and ) are hematophagous ectoparasites that primarily infest white-tailed deer () and other cervids in the United States. The distribution of deer keds in the northeastern United States and the pathogens they harbor remains relatively unexplored.

Diagnostic Performance of Different Examination Types and Learning Curves of Radiologists for 5G-Based Robot-Assisted Tele-Ultrasonography: A Prospective and Large-Scale Study.

Objective: To investigate the feasibility of remotely providing routine ultrasound (US) examinations to patients using a fifth-generation-based robot-assisted tele-ultrasonography (RATU) system in a real-world setting.

Methods: Between September 2020 and May 2021, we conducted a prospective and large-scale study using the RATU system to provide US examinations for patients on a limited-source island locate. An on-site radiologist on the island performed US examinations, which served as the reference diagnosis.

Liquid nitrogen quenching for efficient Bifunctional electrocatalysts in water Splitting: Achieving four key objectives in one step.

Herein, a novel liquid nitrogen quenching treatment is proposed to achieve multifaceted modulation involving morphological modulation, lattice tensile strain modulation, metal active centre coordination reconstruction and grain boundary construction within a series of intermetallic compounds modified on a carbon substrate (CoFe-550/C, CoNi-550/C and FeNi-550/C, where 550 refers to liquid nitrogen quenching temperature and C refers to the carbon substrate). Noteworthily, the optimising intermediate absorption/desorption process is achieved by multifaceted modulation. Consequently, CoFe-550/C, CoNi-550/C and FeNi-550/C demonstrate considerable overpotential for hydrogen evolution reaction (59.

The efficacy analysis of laparoscopic-assisted Soave procedure for Hirschsprung's disease in neonates and infants within 3 months of age.

To evaluate the efficacy of laparoscopic-assisted Soave procedure of Hirschsprung's Disease (HSCR) in neonates and infants within 3 months of age. Patients with HSCR who were admitted to the Department of Fetal and Neonatal Surgery of Hunan Children's Hospital from June 2012 to July 2020 and underwent laparoscopic-assisted Soave procedure were selected. The clinical manifestations, surgical procedures, postoperative fecal contamination, constipation, enterocolitis, and defecation function were analyzed.

A pilot study of the utility of a hospital-based school program for pediatric patients with cardiac diagnoses.

Introduction: Pediatric patients with complex cardiac diagnoses are at increased risk for physical, cognitive, and developmental complications. Formalized school support [i.e.

High-accuracy spatial prediction of soil pollutants and their speciation in strong human-affected areas.

Strong human activities greatly challenge the high-accuracy spatial prediction of soil pollutants and their speciation. This study first determined three auxiliary variables of soil total arsenic (TA) in a typical strong human-affected area, namely in-situ portable X-ray fluorescence (PXRF) TA calibrated by robust geographically weighted regression (RGWR), atmospheric deposition information simulated by atmospheric diffusion model (AERMOD), and land-use types. Then, robust residual cokriging with the above three auxiliary variables (RRCoK-RCPXRF/AD/LUT) was proposed to spatially predict soil TA.

Somy evolution in the honey bee infecting trypanosomatid parasite Lotmaria passim.

Lotmaria passim is a ubiquitous trypanosomatid parasite of honey bees nestled within the medically important subfamily Leishmaniinae. Although this parasite is associated with honey bee colony losses, the original draft genome-which was completed before its differentiation from the closely related Crithidia mellificae-has remained the reference for this species despite lacking improvements from newer methodologies. Here, we report the updated sequencing, assembly, and annotation of the BRL-type (Bee Research Laboratory) strain (ATCC PRA-422) of Lotmaria passim.

Development and validation of a potential risk area identification model for hand, foot, and mouth disease in metropolitan China.

Maximum Entropy model (MaxEnt), as a machine learning algorithm, is widely used to identify potential risk areas for emerging infectious diseases. However, MaxEnt usually overlooks the influence of the optimal selection of spatial grid scale and the optimal combination of factor information on identification accuracy. Furthermore, the internal level information of factors is closely related to the potential risk of disease occurrence but is rarely applied to enhance MaxEnt's accuracy.

Effects of Inosine-5'-monophosphate Dehydrogenase (IMPDH/GuaB) Inhibitors on Growth in Standard and Modified Culture Conditions.

's inosine-5'-monophosphate dehydrogenase (IMPDH, GuaB encoded by the gene) is a potential therapeutic target. GuaB is necessary for replication in mammalian hosts but not in standard laboratory culture conditions. Therefore, we cannot test novel GuaB inhibitors against without utilizing mammalian infection models.

Static and temporal dynamic alterations of local functional connectivity in chronic insomnia.

Several studies have revealed altered intrinsic neural activity in chronic insomnia (CI). However, the temporal variability of intrinsic neural activity in CI is rarely mentioned. This study aimed to explore static and temporal dynamic alterations of regional homogeneity (ReHo) in CI and excavate the potential associations between these changes and clinical characteristics.

Transcriptional Regulation of De Novo Lipogenesis by SIX1 in Liver Cancer Cells.

De novo lipogenesis (DNL), a hallmark of cancer, facilitates tumor growth and metastasis. Therapeutic drugs targeting DNL are being developed. However, how DNL is directly regulated in cancer remains largely unknown.

Plantaginis Semen Ameliorates Hyperuricemia Induced by Potassium Oxonate.

Plantaginis semen is the dried ripe seed of L. or Willd., which has a long history in alleviating hyperuricemia (HUA) and chronic kidney diseases.

Does cytomegalovirus infection and antiviral therapy affect prognosis of biliary atresia? A real-world retrospective cohort study.

To explore the impacts of cytomegalovirus (CMV) infection and antiviral treatment (AVT) on native liver survival (NLS) in biliary atresia (BA) infants. This retrospective cohort study included infants diagnosed as BA between January 2015 and December 2021 at Hunan Children's Hospital. CMV infection was defined by DNA polymerase chain reaction alone (DNA data set) and combination of DNA and immunoglobulin M (CMV data set).

Harnessing Workplace Ostracism: Unleashing Proactive Behavior through Work Focus and Visionary Leadership.

Differing from prior studies which explored workplace ostracism's negative impacts, in this study, we try to explore ways to mitigate and harness workplace ostracism to encourage proactive behavior. By drawing on regulatory focus theory, we propose that workplace ostracism can increase proactive behavior via enhanced promotion focus and prevention focus. We collected questionnaire data at multiple time points from employees in private enterprises in China, and a structural equation model was primarily used to test the proposed model.

Cobalt nanoparticles intercalation coupled with tellurium-doping MXene for efficient electrocatalytic water splitting.

Nowadays, the inherent re-stacking nature and weak d-p hybridization orbital interactions within MXene remains significant challenges in the field of electrocatalytic water splitting, leading to unsatisfactory electrocatalytic activity and cycling stability. Herein, this work aims to address these challenges and improve electrocatalytic performance by utilizing cobalt nanoparticles intercalation coupled with enhanced π-donation effect. Specifically, cobalt nanoparticles are integrated into VC MXene nanosheets to mitigate the re-stacking issue.

Combination of Pirfenidone and Andrographolide Ameliorates Hepatic Stellate Cell Activation and Liver Fibrosis by Mediating TGF-/Smad Signaling Pathway.

Background: Biliary atresia (BA) is a devastating congenital disease characterized by inflammation and progressive liver fibrosis. Activation of hepatic stellate cells (HSCs) plays a central role in the pathogenesis of hepatic fibrosis. Our study aimed to investigate the pharmacological effect and potential mechanism of pirfenidone (PFD) and andrographolide (AGP) separately and together on liver fibrosis of BA.

polysaccharides ameliorates cecal ligation and puncture-induced sepsis by inhibiting the cGAS-STING signaling pathway.

() is an ancient and widely used traditional Chinese medicine with good efficacy in clearing heat and detoxifying action. Studies suggest that Polysaccharides (GUP), one of the major components of has anti-inflammatory, anti-cancer and hepatoprotective effects., but its exact molecular mechanism has not been explored in depth.