Publications by authors named "Guang Jun Yu"
Background: Gut microbiota alterations have been implicated in the pathogenesis of coronavirus disease 2019 (COVID-19). This study aimed to explore gut microbiota changes in a prospective cohort of COVID-19 children and their asymptomatic caregivers infected with the severe acute respiratory syndrome coronavirus type 2 (SARS-CoV-2) Omicron variant.
Methods: A total of 186 participants, including 59 COVID-19 children, 50 asymptomatic adult caregivers, 52 healthy children (HC), and 25 healthy adults (HA), were recruited between 15 April and 31 May 2022.
Article Synopsis
- * Traditional tests like RT-PCR are time-consuming and require lab facilities, while a new point-of-care SERS (Surface-Enhanced Raman Scattering) detection platform can identify the virus in just 5 minutes using a handheld device.
- * This new method targets the SARS-CoV-2 spike protein and accurately detects the virus and its variants without interfering with other coronaviruses or influenza A, making it a strong candidate for rapid diagnostic use.
Objective: To evaluate the efficacy and safety of fecal microbiota transplantation (FMT) in functional gastrointestinal disorders (FGIDs) in children with abdominal bloating and changes in their gut microbiome and metabolome.
Methods: Twelve pediatric FGID patients with predominant abdominal bloating who underwent FMT were enrolled in the study. Fourteen healthy controls and four stool donors were included for analysis.
Background: Asthma has been a global problem, especially in children. We aim to evaluate the contemporary prevalence and influencing factors of asthma among children aged 3-7 years in Shanghai, China.
Methods: A random sample of preschool children was included in this study.
Background: Hand, foot, and mouth disease (HFMD) is a common infectious disease in childhood caused by an enterovirus (EV), and which is principally seen in children under 5 years of age. To promote diagnostic awareness and effective treatments, to further standardize and strengthen the clinical management and to reduce the mortality of HFMD, the guidelines for diagnosis and treatment have been developed.
Methods: National Health Commission of China assembled an expert committee for a revision of the guidelines.