Pseudopterosin A ameliorates ischaemia-induced brain injury by acting on Akt signalling pathway.

Introduction: Brain injury caused by ischaemic stroke is a major cause of disability and death throughout the world. The present study evaluates the neuroprotective effect of pseudopterosin A (PtA) against ischaemia-induced brain injury.

Material And Methods: Ischaemia was induced by pMCAO model, and rats were separated in to three groups.