Publications by authors named "Guanchao Xie"
Objective: This study aimed to evaluate CTF1 expression in glioma, its relationship to patient prognosis and the tumor immune microenvironment, and effects on glioma phenotypes to identify a new therapeutic target for treating glioma precisely.
Methods: We initially assessed the expression of CTF1, a member of the IL-6 family, in glioma, using bioinformatics tools and publicly available databases. Furthermore, we examined the correlation between CTF1 expression and tumor prognosis, DNA methylation patterns, m6A-related genes, potential biological functions, the immune microenvironment, and genes associated with immune checkpoints.
Article Synopsis
- Chronic subdural hematoma (CSDH) is a common condition that can recur after surgery, leading to pain for patients and increased costs for families and healthcare systems due to a lack of accurate prediction methods.
- This study aimed to leverage machine learning techniques to develop predictive models that assess the risk of CSDH recurrence post-surgery, enhancing outcomes for both patients and the healthcare system.
- The research involved analyzing data from 133 patients, where the support vector machine model using clinical-radiomics features was found to be the most effective at predicting recurrence, showing strong accuracy and improved predictive capabilities through feature selection.
A heritable form of SMARCE1-related meningiomas with clinical implications.
J Neuropathol Exp Neurol
January 2025