Publications by authors named "Guan-liang Wang"
Research progress on the development of hepatocyte growth factor/c-Met signaling pathway in gastric cancer: A review.
World J Gastrointest Oncol
August 2024
Article Synopsis
- Hepatocyte growth factor (HGF) and its receptor c-Met are important for understanding and treating gastric cancer (GC), a common type of cancer.
- The HGF/c-Met signaling pathway helps cancer cells grow, move, and spread, making it a key focus for new treatments.
- This review looks at the latest research on how HGF/c-Met works in GC and suggests new ways to target this pathway for better treatment options.
[Effects of ursolic acid on c-Cbl-associated protein expression in 3T3-L1 adipocytes with insulin resistance].
Zhong Xi Yi Jie He Xue Bao
August 2012
Objective: To observe the effects of ursolic acid (UA) on insulin resistance and cell differentiation in 3T3-L1 adipocytes and to explore the mechanisms.
Methods: 3T3-L1 adipocytes were cultured in Dulbecco's modified Eagle's medium (DMEM) supplemented with glucose (25 mmol/L) and insulin (10(-6) mol/L) to induce insulin resistance. After culture, glucose consumption of the adipocytes was detected by glucose oxidase method and glucose uptake was detected by using tritium-marked glucose.
Objective: To explore the effects and mechanism of ursolic acid in improving hepatic insulin resistance in KKAy mice with spontaneous type 2 diabetes.
Methods: Thirty-five KKAy mice were divided into five groups according to the randomized block design, namely, control, rosiglitazone, fenofibrate, and high- and low-dose ursolic acid groups with seven mice in each group. C57BL/6J mice were used as the normal control group.
Aim: To analyze the literature on the use of Chinese herbal medicines for the treatment of cholecystitis.
Methods: The literature on treatment of cholecystitis with traditional Chinese medicines (TCM) was analyzed based on the principles and methods described by evidence-based medicine (EBM). Eight databases including MEDLINE, EMbase, Cochrane Central (CCTR), four Chinese databases (China Biological Medicine Database, Chinese National Knowledge Infrastructure Database, Database of Chinese Science and Technology Periodicals, Database of Chinese Ministry of Science and Technology) and Chinese Clinical Registry Center, were searched.
Background: The conventional therapy for arteriosclerosis obliterans (ASO) is Western medicine. However, it has some adverse effects and does not respond to some patients, and it is also very expensive.
Objective: To evaluate the efficacy of integrated traditional Chinese (TCM) and Western medicine (WM) in treatment of ASO.
[A rare vascular malformation of the lung: discussion of the CT findings and nomenclature].
Nan Fang Yi Ke Da Xue Xue Bao
February 2010
Article Synopsis
- Scientists looked at 4 cases where a part of the lung didn't have its usual blood supply, which normally comes from the pulmonary artery.
- They used special CT scans to find out what was happening in the lungs, noticing some volume loss and cloudy areas.
- They concluded that this problem has specific signs on the scans, and they suggested calling it "local absent pulmonary artery" to better describe what’s wrong.