HDAC6 dysfunction contributes to impaired maturation of adult neurogenesis in vivo: vital role on functional recovery after ischemic stroke.

Background: Promoting post-stroke neurogenesis has long been proposed to be a therapeutic strategy for the enhancement of functional recovery after cerebral ischemic stroke. Despite numerous approaches have been widely reported the proliferation or differentiation of the neurogenic population therapeutic strategies by targeting adult neurogenesis not yet to be successfully clarified in clinical settings. Here, we hypothesized that alterations in microenvironment of the ischemic brain might impede the functional maturation of adult newly generated neurons that limits functional recovery after stroke.

The effect of adding Bi on the performance of a newly developed iron-copper redox flow battery.

In this paper, we propose a new, abundant, cost-effective, non-toxic, and environmentally benign iron-copper redox flow battery (Fe/Cu RFB), which employs Fe/Fe and Cu/Cu as the positive and negative electrolytes, respectively. The effect of graphite felt (GF) electrode modification and addition of Bi into the electrolytes on the performance of the Fe/Cu RFB were investigated. It was found that the cell containing Bi in the electrolytes revealed higher coulombic efficiency (89.

Hospital-based integrated diabetes care management: an overview.

To provide continuous, accessible, and quality care, a diabetes share-care program has been in place in Taiwan for several years. Lukang Christian Hospital, a member of the diabetes share-care network, endeavors to provide "patient-centered" care aimed at increasing care quality and reducing diabetic complications. Information technology has been employed by the hospital for monitoring care quality and analyzing cost-effectiveness.