Cytotoxicity and Apoptosis Induction of 6,7-Dehydroroyleanone from Bark Essential Oil in Hepatocellular Carcinoma Cells.

The objective of the present study is to evaluate the cytotoxicity of essential oil and its phytochemical on the Hep G2 cell line (human hepatocellular carcinoma). Bark essential oil has significant cytotoxicity to Hep G2 cells, and S3 fraction is the most active fraction in cytotoxicity to Hep G2 cells among the six fractions. The diterpenoid quinone, 6,7-dehydroroyleanone, was isolated from the active S3 fraction by bioassay-guided isolation.

Cross-Domain Transfer Learning for PCG Diagnosis Algorithm.

Cardiechema is a way to reflect cardiovascular disease where the doctor uses a stethoscope to help determine the heart condition with a sound map. In this paper, phonocardiogram (PCG) is used as a diagnostic signal, and a deep learning diagnostic framework is proposed. By improving the architecture and modules, a new transfer learning and boosting architecture is mainly employed.

Antiplatelet drug ticagrelor delays gastric ulcer healing in rats.

Adenosine diphosphate P2Y receptor antagonist clopidogrel is not sufficiently safe for the gastric mucosa in patients with high risk of peptic ulcer, since it may impair healing of gastric erosions. However, the safety of the novel P2Y receptor antagonist ticagrelor in the gastric mucosa has not been elucidated to date. The present study aimed to examine whether ticagrelor delays gastric ulcer healing and to elucidate the involved mechanisms.

Multiplex congruence network of natural numbers.

Congruence theory has many applications in physical, social, biological and technological systems. Congruence arithmetic has been a fundamental tool for data security and computer algebra. However, much less attention was devoted to the topological features of congruence relations among natural numbers.

Synthesis of magnetofluorescence Gd-doped CuInS2/ZnS quantum dots with enhanced longitudinal relaxivity.

In this paper, we describe the rapid microwave-assisted synthesis of Gd(3+)-doped CuInS2 (Gd:CIS) quaternary quantum dots (q-dots), which integrate the functions of optical fluorescence and magnetic resonance imaging. Through passivation of ZnS shells around Gd:CIS cores, high-quality and robust photostable Gd:CIS/ZnS core/shell q-dots with enhanced quantum yields were obtained. The intensity and peak-to-peak linewidth of the electron spin resonance (EPR) signal were found to vary depending on the Gd(3+) concentration of Gd:CIS/ZnS.

Chaos of elementary cellular automata rule 42 of Wolfram's class II.

In this paper, the dynamics of elementary cellular automata rule 42 is investigated in the bi-infinite symbolic sequence space. Rule 42, a member of Wolfram's class II which was said to be simply as periodic before, actually defines a chaotic global attractor; that is, rule 42 is topologically mixing on its global attractor and possesses the positive topological entropy. Therefore, rule 42 is chaotic in the sense of both Li-Yorke and Devaney.

Geographical effect on small-world network synchronization.

We investigate the geographical effect on the synchronization of small-world oscillator networks. We construct small-world geographical networks by randomly adding links to one- and two-dimensional regular lattices, and we find that the synchronizability is a nonmonotonic function of both the coupling strength and the geographical distance of randomly added shortcuts. Our findings demonstrate that the geographical effect plays an important role in network synchronization, which may shed some light on the study of collective dynamics of complex networks.