Effect of hyperbaric oxygen on post-stroke depression.

Background: In patients with post-stroke depression (PSD) in diabetes, the situation may be more complex, requiring simultaneous treatment of blood glucose, depressive symptoms, and neurological dysfunction. Hyperbaric oxygen (HBO) therapy can improve tissue oxygen content and improve the situation of ischemia and hypoxia, thus playing a role in protecting brain cells and restoring the function of brain cells. However, there are few studies on HBO therapy for patients with PSD.

A meta-analysis comparing regorafenib with TAS-102 for treating refractory metastatic colorectal cancer.

Objective: We performed this meta-analysis to compare the efficacy and toxicity of regorafenib and TAS-102.

Methods: Electronic databases were searched to identify studies comparing the efficacy and safety of regorafenib and TAS-102 in patients with chemotherapy-refractory metastatic colorectal cancer using pooled analyses.

Results: Three clinical trials were included in this analysis.