Publications by authors named "Guan Ting Zhang"
Article Synopsis
- - The study analyzed complete genome sequences of SARS-CoV-2 collected from 177 COVID-19 patients at a hospital in Guangzhou, focusing on the diversity and mutation characteristics of the virus between October 2020 and May 2021.
- - Key findings indicated a peak in imported COVID-19 cases from the U.S. in May 2021, with significant variants like B.1.1.7 and B.1.351 identified alongside unique mutations not previously documented in major databases.
- - The research highlighted that the ORF1a protein had the highest mutation density, and the D614G mutation in the spike protein was most common, suggesting the emergence of diverse lineages and the potential for further viral evolution
[Expression of Death Associated Protein Kinase 1 in Chronic Lymphocytic Leukemia].
Zhongguo Shi Yan Xue Ye Xue Za Zhi
April 2017
Objective: To explore the expression of death-associated protein kinase 1(DAPK1) in chronic lymphocytic leukemia(CLL).
Methods: The DAPK1 expression was studied by means of MEC1 cells and B lymphocytes from blood samples of the patients with CLL. The quantitative detection of mRNA and Western blot were used to detecte the expression of DAPK1 and autophagy-related genes at both mRNA and protein levels.
[PTK7 mRNA and protein expression level in serum of patients with acute lymphocytic leukemia and its clinical significance].
Zhongguo Shi Yan Xue Ye Xue Za Zhi
October 2014
The purpose of this study was to detect the serum PTK7 level of patients with acute lymphocytic leukemia, and to reveal its clinical value for diagnosis of diseases. A total of 136 patients diagnosed as acute lymphocytic leukemia from May 2012 to April 2014 in our hospital were enroled in this study and were divided into the L1 group (n = 42), L2 (n = 45) and L3 group (n = 49) according cytomorphology, and 48 normal children were selected as control group. Fluorescence quantitative PCR was used to detect mRNA level of PTK7 in peripheral blood mononuclear cells, and Western blot was used to detect PTK7 protein expression.
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