Publications by Gu-Ijie Ma | LitMetric

Publications by authors named "Gu-Ijie Ma"

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Influence of JuA in evoking communication changes between the small intestines and brain tissues of rats and the GABAA and GABAB receptor transcription levels of hippocampal neurons.

Xi-Xi Wang Gu-Ijie Ma Jun-Bo Xie Guang-Chang Pang

J Ethnopharmacol

January 2015

Article Synopsis

Jujuboside A (JuA), a key component of semen ziziphi spinosae, is shown to enhance sleep by reducing spontaneous activity, speeding up sleep onset, and increasing total sleep time.
In laboratory tests involving rat tissues, JuA was found to lower levels of several pro-inflammatory cytokines after treatment, suggesting a pathway through which it exerts its sedative effects.
Additionally, JuA treatment altered the expression of GABA receptor mRNAs in hippocampal neurons, indicating that it influences both GABA signaling and cytokine communication in the brain to enhance sleep quality.

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