Publications by authors named "Gu-Hee Kim"
Article Synopsis
- Embryonic stem cells (ESCs) need to be kept undifferentiated, and they can grow on mouse STO fibroblast cells, which help by secreting important cytokines.
- Infection of STO cells with a specific adenovirus (rAd-dnIκB) inhibits the NF-κB signaling pathway, resulting in a notable decrease in the growth and colony formation of mouse ESCs (mESCs).
- The infected STO cells showed increased levels of BMP4, which, when present in excess, inhibited the proliferation of mESCs, indicating that BMP4 plays a repressive role in maintaining ESC growth.
