Introduction: Paraoxonase (PON1) is one of enzymes participating in antioxidative defence mechanism, which protects the organism from the results of action of reactive oxygen species. PON1 is an esterase contained in plasma high density lipoproteins (HDL) which protects HDL from peroxidation and plasma membranes from free radical injury. PON1 serum activity is diminished in some diseases (atherosclerosis, diabetes, coronary artery disease) and after cardiosurgery operations.
View Article and Find Full Text PDFIntroduction: Reactive oxygen species (ROS) generated after the trauma caused by surgical intervention, have the capacity to react in an indiscriminate manner leading to damage to almost any cellular component (proteins, nucleid acids) and to lipid peroxidation. The assessment of ROS generation intensity process may help in understanding of molecular processes observed in the intracellular environment after operations. The evaluation of antioxidative level may give an answer about the efficiency of antioxidative defence mechanism.
View Article and Find Full Text PDFDynamic development in modern medicine permanently brings the modifications of operation techniques. Both closure and non-closure of the peritoneum after gynecologic operations has been discussed recently. According to clinical observations provided by many authors, the controversial problem of non-closure of the peritoneum is still under discussion.
View Article and Find Full Text PDFThe study was carried out on 7 human placental cotyledons. Placental perfusions performed by Schneider method modified by Miller were conducted for 180 min. assessment of arterial and venous pressure in fetal blood was performed.
View Article and Find Full Text PDFThe study was carried out on 7 human placental cotyledons. Placental perfusions performed by Schneider method modified by Miller were conducted for 180 min. Assessment of arterial and venous pH in maternal and fetal blood was performed.
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