Publications by authors named "Gry Helen Enger Syverstad"
Article Synopsis
- Research indicates an association between hormonal changes in the HPG axis and cognitive decline in Alzheimer's disease, particularly post-menopause or andropause.
- Studies on transgenic mice with AD help enhance understanding of the disease's underlying mechanisms, focusing on the expression of gonadotropin-releasing hormone (Gnrh) and its receptor (Gnrhr).
- Treatment with a Gnrh analog (Leuprorelin acetate) effectively downregulated Gnrh and Gnrhr mRNA levels in these mice, showing potential for hormonal treatments in addressing Alzheimer's pathology.
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