The incidence of multiple meningiomas--do solitary meningiomas exist?

Since the advent of computed tomography (CT) the recognition of the occurrence of multiple intracranial meningiomas (MIM) in the same individual has been on the increase. In our material the incidence of MIM at first assessment of CT films was 20%, with distant multiplicity prevailing over the regional one. This incidence will probably change in the course of time as MIM develop not only concurrently but also consecutively.

Cystic meningiomas.

Four cases of cystic meningiomas were found among 194 meningiomas diagnosed by computed tomography (CT) and operated on during a 7 year period, an incidence of 2%. The cysts were in all cases peritumoral. The cyst's wall was the brain itself, and the ependymal ventricular wall was part of their medial boundary.

Metastasis of invasive carcinoma of the breast to an extradural meningioma of the cranial vault.

A case of metastasizing invasive carcinoma of breast to an expanding extradural frontal meningioma is presented. The peculiar tendency of meningioma to be the host tumor for carcinoma is discussed. The literature pertaining to such rare occurrences is reviewed.

Acute spinal extradural haematoma.

Two cases of acute spinal extradural haematoma (ASEH) are presented. Regression of neurological deficit is dependent on early diagnosis and urgent surgical decompression. A review of the literature is included.

Spinal cord compression in Paget's disease of bone with reference to sarcomatous degeneration and calcitonin treatment.

Four cases of spinal cord compression stemming from Paget's disease of bone tissue are reported. Sarcomatous degeneration was proved in one case and in another one malignancy was deduced by computed tomography (CT) scanning. Clinical and radiologic manifestations as well as surgical management are discussed.

Recurrence of intracranial meningiomas: the role played by regional multicentricity. Part 2: Clinical and radiological aspects.

Globular single meningiomas are generally regarded as benign tumors that can be completely removed. Nevertheless, after a total macroscopic resection including the insertion zone (Grade 1 operation according to Simpson's classification), the incidence of recurrence ranged from 9% to 14% at the 5-year follow-up review. The authors have shown that single meningiomas represent only the visible predominant growth in the midst of a wide neoplastic field in the dura mater.

Hyperhidrosis and its surgical treatment.

111 sections of high thoracic sympathectomies in 60 cases suffering from primary palmar hyperhidrosis are reported. Surgical results and postoperative complications are discussed in detail. Complications were few in number and were of a transitory nature.

A comparison of lithium effects on human brain and rat brain noradrenaline-sensitive adenylate cyclase.

Lithium (Li) is a drug with numerous biochemical effects. Many of these biochemical effects occur only at high Li concentrations, or disappear after chronic Li treatment. Such effects are probably not related to Li's mechanism of therapeutic action.

Primary cutaneous extravertebral meningioma. Case report.

A case of cutaneous extravertebral meningioma is presented. It was diagnosed in infancy as a lumbar meningocele. Operation was initially refused but was subsequently demanded for cosmetic reasons.

The syndrome of the central L-3-herniated disc with special emphasis on motor involvement.

Literature about the clinical characteristics of herniation of the lumbar intervertebral disc is profuse. Due to their predominant frequency, attention was almost entirely devoted to the L-4 and L-5 prolapses. As clinical accuracy still remains a very important target, specially in departments where myelography is not used for the diagnosis of this entity, the authors thought it of interest to describe the clinical picture of the L-3-herniated disc.

Brain abscess and its surgical management.

A series of 56 patients with brain abscesses who were treated over a period of 23 years is reviewed. Patients with posttraumatic infections were not included. The operative mortality was 11%.

Aneurysmal bone cyst of spine.

Four patients (aged 5, 7, 18, and 42) suffering from spinal cord involvement due to an aneurysmal bone cyst are reported. In two cases only a preoperative radiological diagnosis was made, one of them by a CT scan. Combined surgical and radiological treatments were done in three cases with a follow-up of 16 years in one patient and 9 years in the other two.

Penetrating cranio-cerebral injuries due to unusual foreign bodies.

Seven cases of penetrating cranio-cerebral injury by peculiar foreign bodies are described. The clinical-pathological picture is reported wherever possible. Lack of adequate safety measures and untrained careless handling of instruments were at the root of these tragic accidents.

Incidence, prognostic significance and therapeutic modalities of central nervous system involvement in multiple myeloma.

In 114 patients with systemic malignant gammopathies followed during a 10-year period in the hematology clinic of the Rambam Medical Center, 23 episodes of CNS involvement were recorded. 19 cases with spinal cord compression and 4 cases of intracranial plasmacytomas. Early diagnosis followed by prompt laminectomy and subsequent radiotherapy resulted in complete recovery in 50% and partial improvement in 30% of the patients with spinal cord involvement.

Benign osteoblastoma of vertebral column and skull.

Three cases of benign osteoblastoma in children are reported; two in the spine and one in the occipital bone. clinical, pathological and X-ray appearance are discussed. The importance of complete removal whenever possible is stressed.