Publications by authors named "Grubisic B"

Neuroinvasive flaviviruses such as tick-borne encephalitis virus (TBEV) and West Nile virus (WNV) are widely distributed in continental Croatian regions. We analyzed clinical characteristics, laboratory parameters, and molecular epidemiology of neuroinvasive flavivirus infections in eastern Croatia. A total of 43 patients with confirmed flavivirus infection hospitalized from 2017 to 2023 were included in the study.

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Article Synopsis
  • - Sodium imbalance is a frequent issue in COVID-19, often caused by hormonal disruptions, particularly involving conditions like hypothyroidism and hypocortisolism, which can both lead to lower sodium levels (hyponatremia).
  • - Hypocortisolism, resulting from adrenal or pituitary issues, affects the kidneys' ability to excrete water properly and increases the secretion of antidiuretic hormone (ADH), further diluting sodium levels.
  • - The review emphasizes that the relationship between COVID-19 and sodium imbalance is complicated by factors like the renin-angiotensin-aldosterone system (RAAS) being impacted by the virus, highlighting the need for more research to better manage these disturbances in affected
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Growth differentiation factor 15 (GDF-15) is a stress-induced cytokine associated with acute and chronic inflammatory states. This prospective observational study aimed to investigate the prognostic roles of GDF-15 and routine clinical laboratory parameters in COVID-19 patients. Upon the admission of 95 adult hospitalized COVID-19 patients in Croatia, blood analysis was performed, and medical data were collected.

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Article Synopsis
  • Antidiuretic hormone (ADH) release from the posterior pituitary can lead to hyponatremia if not properly regulated, a condition known as SIADH.
  • A case study details a 67-year-old male who developed SIADH symptoms after taking ciprofloxacin for prostatitis, with low serum sodium levels confirming the condition.
  • After discontinuing ciprofloxacin and restricting fluids, his sodium levels improved significantly within four days, underscoring the need for awareness among healthcare providers about the potential side effects of this antibiotic.
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The COVID-19 pandemic has revealed a significant association between SARS-CoV-2 infection and diabetes, whereby individuals with diabetes are more susceptible to severe disease and higher mortality rates. Interestingly, recent findings suggest a reciprocal relationship between COVID-19 and diabetes, wherein COVID-19 may contribute to developing new-onset diabetes and worsen existing metabolic abnormalities. This narrative review aims to shed light on the intricate molecular mechanisms underlying the diabetogenic effects of COVID-19.

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The helminth infection caused by is widespread in tropical regions, but rare in European countries. Unfamiliarity with the disease and diagnostic obstacles could contribute to its lethal outcome. Frequent use of corticosteroids during the COVID-19 pandemic could increase its significance.

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