Publications by authors named "Grossetti E"

Article Synopsis
  • Social vulnerability significantly impacts perinatal medical risks for both mothers and fetuses, with one-third of maternal deaths between 2016-2018 linked to it.
  • A considerable portion of these deaths (73%) involved sub-optimal care, with a higher chance of avoidability (63%) compared to women without social vulnerability (56%).
  • The study highlights the importance of enhancing the interaction between socially vulnerable women and healthcare systems to reduce maternal mortality and improve outcomes.
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Article Synopsis
  • * The majority of cases occurred during labor, with an average time from symptom onset to death being about 4 hours and 45 minutes, highlighting the rapid progression of the condition.
  • * Preventability was suggested for 35% of these deaths, indicating opportunities for improvement in medical skills, communication, and health care organization; autopsies were conducted in 38% of the cases.
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Objective: To learn lessons for maternity care by scrutinizing postpartum hemorrhage management (PPH) in cases of PPH-related maternal deaths in France and the Netherlands.

Methods: In this binational Confidential Enquiry into Maternal Deaths (CEMD), 14 PPH-related maternal deaths were reviewed by six experts from the French and Dutch national maternal death review committees regarding cause and preventability of death, clinical care and healthcare organization. Improvable care factors and lessons learned were identified.

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The objective of this review was to assess benefits and harms of different management options for induction of labor and obtaining of uterine vacuity in case of fetal death beyond of 14 weeks of gestation. In second-trimester, the data are numerous but low methodological quality. In terms of efficiency (induction-expulsion time and uterine evacuation within 24 hours rate) and tolerance in the absence of antecedent of caesarean section, the best protocol for induction of labor in the second-trimester of pregnancy appears to be mifepristone 200mg orally followed 24-48 hours later by vaginal administration of misoprostol 200 to 400 μg every 4 to 6 hours.

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Objective: To assess the effectiveness and the safety of prevention and treatment of iron deficiency anemia during pregnancy.

Methods: French and English publications were searched using PubMed and Cochrane library.

Results: Early screening of iron deficiency by systematic examination and blood analysis seemed essential.

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Article Synopsis
  • * Conducted at a hospital in western French Guyana from 1992 to 2004, the retrospective cohort study included 29 women and examined outcomes like pre-eclampsia, preterm delivery, and neonatal mortality.
  • * Results indicated that prophylactic transfusions reduced vaso-occlusive crises and preterm deliveries but led to an increase in intrauterine growth restriction, suggesting a mixed impact on complications, warranting further research through a randomized study.
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Objective: To assess in current practice the application of our protocol of using fetal pulse oximetry during labor, to evaluate whether fetal scalp blood sampling can be reduced and to determinate reliability of fetal pulse oximetry on the prediction of poor neonatal outcomes.

Study Design: Prospective observational unicenter cohort including 449 patients during two years. All pregnancies were singleton, greater than or equal to 37 weeks' gestation, cephalic presentation, and had non reassuring fetal heart rate.

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Objective: To assess the risk of uterine rupture of the scarred uterus according to mode of delivery in subsequent births recorded as spontaneous labour, labour induced by oxytocin, labour after ripening with prostaglandin E2, and planned cesarean section.

Methods: Retrospective study of 2,128 births with a low transversal scar after a previous cesarean section. The study population was realised in a level III university hospital from 1995 to 2003.

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Objective: To determine whether morbidly obese women have an increased risk of pregnancy complications and adverse perinatal outcome.

Methods: In a retrospective study, 2472 women with morbid obesity, defined as a body mass index (BMI) more than 40 were compared with normal weight women (BMI 20-25). Fisher and Student tests were used for statistical analysis.

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We are introducing a simplified cure, derived from Alteimeier's intervention, of rectal prolapse by perineal way resection using a linear cutting stapler. It's a reproducible, quick and easy technique, which permits the elderly patients to come back in their middle of life rapidly with few complications.

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