Effect of thermal fluctuations on the nontrivial topology of the + superconducting phase.

The behavior of the topological index (TI), characterizing the properties of superconducting phases of quasi-two-dimensional systems with nontrivial topology, is investigated depending on the temperature and system parameters. For this purpose, a method of calculating the TI, based on a self-consistent functional-integral theory, is proposed. The chiral + superconducting phase of a quasi-two-dimensional model with effective attraction between the electrons located at the nearest sites of a triangular lattice is considered.

Thermal fluctuations in superconducting phases with chiral+ iandsymmetry on a triangular lattice.

The behavior of thermal fluctuations of a superconducting order parameter with extendedand chiral+ isymmetry is investigated. The study is carried out on a triangular lattice within the framework of the quasi-two-dimensional single-band model with attraction between electrons at neighboring sites. The method of consistent consideration of the order parameter fluctuations and the charge carrier scattering by fluctuations of coupled electron pairs, based on the theory of functional integration is used.

Effect of atomic disorder on the magnetic phase separation.

The effect of disorder on the magnetic phase separation between the antiferromagnetic and incommensurate helical [Formula: see text] and [Formula: see text] phases is investigated. The study is based on the quasi-two-dimensional single-band Hubbard model in the presence of atomic disorder (the [Formula: see text] Anderson-Hubbard model). A model of binary alloy disorder is considered, in which the disorder is determined by the difference in energy between the host and impurity atomic levels at a fixed impurity concentration.

Clinical outcomes from maximum-safe resection of primary and metastatic brain tumors using awake craniotomy.

Objective: To retrospectively analyze outcomes in patients undergoing awake craniotomies for tumor resection at our institution in terms of extent of resection, functional preservation and length of hospital stay.

Patients And Methods: All cases of adults undergoing awake-craniotomy from September 2012-February 2015 were retrospectively reviewed based on an IRB approved protocol. Information regarding patient age, sex, cancer type, procedure type, location, hospital stay, extent of resection, and postoperative complications was extracted.

Brain-targeted delivery of doxorubicin using glutathione-coated nanoparticles for brain cancers.

Objectives: To prepare and characterize in vitro a novel brain-targeted delivery of doxorubicin using glutathione-coated nanoparticles (NPs) for the treatment of brain cancer.

Methods: Doxorubicin-loaded NPs were prepared by the nanoprecipitation method using PLGA-COOH (dl-lactide-co-glycolide). The NPs were coated with a glutathione-PEG conjugate (PEG-GSH) in order to target delivery to the brain.

Preparation and characterization of microemulsion of cilostazol for enhancement of oral bioavailability.

Cilostazol is a promising drug for antiplatelet combination therapy that is very important for treatment for various cardiovascular disorders. However, oral delivery of this drug is greatly impeded by the poor solubility in aqueous solutions. The aim of this study was to develop microemulsion (ME) delivery system capable of improving the drug bioavailability.

Preparation and characterization of methylene blue nanoparticles for Alzheimer's disease and other tauopathies.

Methylene blue (MB) has been shown to slow down the progression of the Alzheimer's disease (AD) and other tauopathies; however distribution of MB into the brain is limited due its high hydrophilicity. In this study, we aimed to prepare novel hydrophobic glutathione coated PLGA nanoparticles to improve bioavailability of MB in the brain. Glutathione coated poly-(lactide-co-glycolide) (PLGA-b-PEG) nanoparticles (NPs) were prepared and tested in two different cell culture models of AD expressing microtubule associated protein tau (tau).

[Treatment of terminal forms of icterohemorrhagic leptospirosis].

Complex therapy, using hemosorption in combination with hemodialysis and hyperbaric oxygenation, was suggested for the treatment of patients with terminal stages of icterohemorrhagic leptospirosis. Such complex therapy decreased the mortality rate of patients with terminal stages of icterohemorrhagic leptospirosis from 76-96% to 18-22% and reduced the in-hospital stay from 60-80 to 35-40 days.

[A clinical case of botulism].

A patient with botulism (type E) has been subject to complex therapy, which involved specific serotherapy, infusion therapy, and controlled lung ventilation with the following assisted lung ventilation.

Morphology of blood cells and the surface of charcoal by scanning electron microscopy during haemoperfusion in patients with hepatorenal syndrome.

The surface structure of non-spherical natural and spherical polymeric charcoal as well as the composition of blood cells in peripheral blood was studied in 52 patients with hepatorenal syndrome using the scanning electron microscope. Our data have allowed us to conclude that the optimal varieties of charcoal in respect of haemocompatibility are non-coated polymeric charcoals with spherical granules. Moreover, these varieties are characterised by an increased ability to absorb deformed erythrocytes.

[Effect of lyophilization on IgG aggregation processes in immunoglobulin preparations].

The conditions of the lyophilization of immunoglobulins as prescribed by the current technical regulations lead to the increased content of aggregated molecules in the preparation. The storage of the bulk preparation for two months after drying considerably decreases the content of aggregations. The authors believe it to be expedient to introduce the stage of storage after drying into the regulations for drying immunoglobulin preparations in the process of their production.

[Dried Escherichia diagnostic agents from live cultures].

The possibility of using selected cultures of opportunistic Escherichia, freeze-dried in a saccharose-gelatine medium, as dried diagnostic reagents. In the agglutination test with Escherichia OK diagnostic sera, both fresh and stored for a period of up to 1 year, these dried diagnostic reagents prepared from live cultures showed the same degree of agglutination as live suspensions of similar Escherichia cultures.