Presence of dengue virus RNA in urine and oral fluid of laboratory-confirmed dengue patients: Implications for wastewater surveillance.

Introduction: Dengue cases in the Americas in 2024 have reached record highs, especially in Brazil. However, surveillance remains suboptimal and new methods are needed to monitor Dengue Virus (DENV) spread. To assess whether wastewater-based epidemiology would be a useful tool, we investigated the presence of DENV RNA in dengue patients' urine and oral fluid from an endemic area to inform how shedding in these fluids occurs and provide insight for wastewater surveillance.

Endothelin A receptor inhibition increases nitric oxide-dependent vasodilation independent of superoxide in non-Hispanic Black young adults.

Young non-Hispanic Black adults have reduced microvascular endothelial function compared with non-Hispanic White counterparts, but the mechanisms are not fully elucidated. The purpose of this study was to investigate the effect of endothelin-1 A receptor (ETR) and superoxide on cutaneous microvascular function in young non-Hispanic Black ( = 10) and White ( = 10) adults. Participants were instrumented with four intradermal microdialysis fibers: ) lactated Ringer's (control), ) 500 nM BQ-123 (ETR antagonist), ) 10 μM tempol (superoxide dismutase mimetic), and ) BQ-123 + tempol.

Comparison of Long-term Outcomes of Heparin Bonded Polytetrafluoroethylene and Autologous Vein Below Knee Femoropopliteal Bypasses in Patients with Critical Limb Ischaemia.

Objective/background: Endovascular first is the preferred therapy approach to critical limb ischaemia (CLI). However, in spite of new endovascular techniques, bypass surgery still plays an important role, especially in patients with complex anatomy in whom endovascular therapy is not considered feasible, or has failed. The goal of this study was to analyse the outcomes of prosthetic or autologous vein for femoropopliteal (P3) bypasses performed under the abovementioned conditions.

The Motor Unit Number Index (MUNIX) in sarcopenic patients.

Introduction: The cause of sarcopenia is still not fully understood. A multifactorial aetiology is discussed. Neurodegenerative aspects in the genesis of sarcopenia, such as loss of motoneurons, have not yet been explored to a sufficient extent.

Langmuir supercells: a mechanism for sediment resuspension and transport in shallow seas.

Recent measurements at a cabled sea-floor node in 15 meters of water off the coast of New Jersey suggest that Langmuir supercells, Langmuir circulations that achieve vertical scales equal to the water depth under extended storms, are an important mechanism for major sediment resuspension events on the extensive shallow shelves off the eastern U.S. coast.

Blood pressure and heart rate dynamics during and after exercise in an unselected population.

It has been suggested that the systolic blood pressure (SBP) response to exercise may be useful in predicting future hypertension. However, controversy exists as to whether the SBP response to exercise in borderline hypertensives is actually greater than normotensives or merely increases equally but from a higher resting value. Our aim was to determine the influence of resting SBP, age and sex on changes of SSP during exercise for both healthy subjects and untreated mild hypertensives.

Short-term strenuous exercise training: effects on blood pressure and hormonal levels in mild hypertension.

The effect of a six-week strenuous exercise training programme (modified Bruce protocol, treadmill, three times per week) on resting and exercising blood pressure, heart rate, plasma catecholamines, chromogranin A, renin activity and aldosterone levels was investigated in 15 patients with mild hypertension. An identical exercise test was conducted at baseline and study close (six weeks). At follow-up, seven to ten days after study close, patients completed an exercise test of equivalent intensity to that at baseline, achieving comparable heart rate levels at maximal exercise.

Sciatica caused by isolated non-Hodgkin's lymphoma of the spinal epidural space: a report of two cases.

Two patients are described in whom sciatica was caused by non-Hodgkin's lymphoma involving the spinal epidural space. Systematic investigation revealed no evidence of lymphoma in other sites.

[Aortobronchopulmonary fistula following a pulmonary contained aortic rupture in patients with a thoracic aortic aneurysm and severe aortic sclerosis].

Rupture of the thoracic aorta is usually widespread and fatal. Rupture limited by the lung and aorto-bronchopulmonary fistula are rare. We report two patients with a contained perforation of the thoracic aorta, who presented with haemoptysis.

Strenuous short-term dynamic exercise: effects on heart rate, blood pressure, potassium homeostasis, and packed cell volume in mild hypertension.

This study examined the effect of strenuous short-term dynamic exercise on the heart rate, blood pressure, plasma potassium and packed cell volume in mildly hypertensive subjects. At baseline a symptom-limited Bruce Exercise Protocol was carried out with blood pressure, heart rate, plasma potassium and packed cell volume measurements at fixed time points at rest and during and after the exercise. After 6 weeks of taking exercise sessions (Bruce protocol) to fatigue three times a week, the subjects were restudied.

[Problems of social adaptation of children in a changing environment (author's transl)].

Results of investigations in the German Democratic Republic, USSR and PR Bulgaria concerning infants going first time to a childrens creech are reviewed. Different phenomenons of social adaptation are shown. Author feels the need to build up social relations of the little child to individuals beyond the family in an early time of life.