Publications by authors named "Groote G"

Introduction: It is debated whether the general population should be screened for kidney disease. This study evaluated whether screening of albuminuria and estimated glomerular filtration rate (eGFR) in a working population should be recommended to detect subjects with chronic kidney disease.

Methods: The unreferred renal insufficiency study is a cross-sectional study in 1,398 workers aged 17-65.

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Background: The use of microalbuminuria (MAU) to screen for cardiovascular and renal risk might be hampered by its intermittent character. This prospective observational study assessed traditional risk factors in presumed healthy workers with intermittent MAU (IMAU) compared to persistent MAU (PMAU).

Methods: A cohort of 239 Belgian workers underwent at least two consecutive occupational check-ups with a median time of 12 months.

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Background: There remains debate about the screening strategies for albuminuria. This study evaluated whether a screening strategy in an apparently healthy population based on basic clinical and biochemical parameters could be more effective than a strategy where screening for albuminuria is performed unselectively.

Methodology/principal Findings: The Unreferred Renal Insufficiency (URI) Study is a cross-sectional study on the prevalence of metabolic risk factors in Belgian workers, volunteering to be screened during a routine yearly occupational check-up.

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Stool samples from Belgian patients suffering from abdominal pain and/or diarrhoea were examined for Cryptosporidium and Giardia. Cryptosporidium-positive samples were genotyped using the 70 kDa heat shock protein and the 60 kDa glycoprotein (GP60) genes: C. hominis was identified in 54.

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Objective: The aim of the study was to determine the extent to which plasma matrix types, diurnal rhythm and sample collection and processing procedures contribute to overall variability of measurements with the INNO-BIA plasma Abeta forms assay.

Methods: Plasma samples from healthy volunteers were collected at BARC-CRI. Analyte concentrations from various plasma matrix types (EDTA, heparin, fluoride) were compared to serum after collection of blood in commercial plastic and glass tubes.

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Background: The main aim of this pilot study was to determine whether the omega-3 status can be improved by the use of a fish oil-enriched spread in a regular diet.

Methods: The study started with an open arm where the participants consumed their regular diets followed by a randomized placebo-controlled arm with the inclusion of a spread which was either fish oil enriched or not (control). After each period,the fatty acid composition of red blood cell (RBC) and plasma phospholipids was determined by standard procedures and the sum of eicosapentaenoic and docosahexaenoic acid calculated.

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The objective of this study was to explore whether time-variant parameter estimation procedures allow modeling and predicting the dynamic growth response of broiler chickens to feed intake in real time. A recursive linear model was used that estimated the model parameters every 24 h based on a fixed number of actual and past measurements (i.e.

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1. Two experiments were conducted to investigate the influence of compensatory growth, induced by early quantitative food restrictions, on the efficiency of nitrogen-retention in two lines of Ross broilers. 2.

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1. An experiment was conducted with male broiler chickens to investigate the effect of different early food restriction programmes on proportional weights and allometric growth coefficients of carcase parts and on pulsatile growth hormone secretion. 2.

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1. An experiment was conducted with broiler chickens to determine the effects of different early food restrictions, strain (Ross 508 and Hybro G) and sex on performance, mortality carcase composition and meat characteristics. 2.

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1. The aim of the study was to determine the ideal ratio of the essential amino acids lysine (Lys), methionine (Met), threonine (Thr), tryptophan (Trp), arginine (Arg), valine (Val) and isoleucine (Ile) and to assess the required dietary lysine concentration for optimum performance in broiler chickens of 2 commercial strains from 20 to 40 d of age. 2.

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Two balance trials were conducted to examine the response in metabolizable energy and metabolizability of both fat and amino acids to graded levels of zinc bacitracin (ZnB; Albac registered trade name of Alpharma, Oslo, Norway) in practical broiler and layer diets varying in their nutrient density. Broiler diets were supplemented with either 0, 20, or 50 mg ZnB/kg and layer diets were supplemented with either 0, 50, or 100 mg ZnB/kg. Each experimental diet was fed to five replicates of four broiler chicks each or nine replicates of individually housed laying hens, respectively.

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1. The present study was conducted to determine the possibility of using low-protein broiler diets supplemented with synthetic amino acids. The effects on performance, carcase composition and nitrogen retention were evaluated.

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1. Medium weight laying hens were used for an assay to determine their isoleucine requirement between 26 and 36 weeks of age and again between 46 and 56 weeks of age. 2.

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Relationships between the ratio of unsaturated to saturated fatty acids (U:S) in the diet and the utilization and AME(n) of added fat were studied using the results of a number of previously reported experiments. Mathematical equations relating fat AME(n), fat utilization, and palmitic, oleic, and linoleic acid utilization to the U:S were calculated for young broiler chicks. Best fit regression equations for added fat utilization and fat AME(n) were exponential, showing fat utilization increased very steeply in the U:S range of 0 to 2.

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1. Brown egg layers and dwarf broiler breeder females were force-moulted by different diets. The relationship between the extent of feather replacement and subsequent laying performance was studied.

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A trial with broiler males, housed in cages, was conducted to determine the effect of (added) dietary fluoride at 0, 200, and 400 mg/kg on performance and bone characteristics and the influence of preconditioning (drying, defatting) on bone-breaking strength. The F administration resulted in a significantly (P less than .05) lower weight gain.

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[Seromucous otitis and atopic allergy].

Ann Otolaryngol Chir Cervicofac

December 1986

The various recent studies conducted are reviewed with the aim of establishing or refuting the hypothesis of a relation between immediate type I allergic reactions and seromucous otitis. Critical analysis of the different publications available is completed by an analysis of a personal series of 58 examinations of serum and secretory IgE levels in children 6 months to 11 years with seromucous otitis. Findings fail to support the hypothesis of type I allergy as a major, primary etiologic factor in seromucous otitis even though this affection can appear as a complication of an allergic diathesis.

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A factorial experiment involving 1,404 day-old Shaver broiler chicks (702 of each sex) assessed the effects of total calcium (Ca) and available phosphorus (AP) and their ratio (Ca: AP) during the starter (0 to 21 days) and finisher (22 to 42 days) periods on general performance, tibia strength, tibia ash, Ca and P content of tibia ash, tibia dyschondroplasia, twisted legs, and total leg abnormalities. Nine starter and nine finisher diets were used with the percentage Ca and AP ranging from .98 to 1.

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A sensitive endogenous enzyme immunoassay involving an anti-human placental alkaline phosphatase (PLAP) monoclonal antibody was used in the screening of sera and tumor extracts of patients with various types of cancer. In sera of breast cancer patients an incidence of 5.2% was recorded.

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To investigate the possible role of type 1 allergy in OME, the immunoglobulin E (IgE) content was determined in 58 middle ear effusions and matched sera, obtained from children with otitis media with effusion (OME). The IgE levels were assayed for IgE by the Phadebas paper radio immunosorbent test (PRIST). Eight cases (14%) showed elevated serum IgE levels, such that an atopic disorder was very likely.

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The efficacy of a heat-inactivated hepatitis B vaccine, 3 micrograms of surface antigen (HBsAg), given at 0, 1, 2, and 5 months, was evaluated in 401 haemodialysis patients in 18 centres by a placebo-controlled, double-blind, randomised trial. The attack-rate of hepatitis B virus (HBV) infections in the control group was 18% over 435 days. The protective efficacy rate of the vaccine was 78% against all HBV infections in the entire study (p = 0.

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This study reports the findings of an electron microscopic search for so-called non-A, non-B nuclear particles in liver biopsies from patients with mainly chronic or prolonged liver disease and from chimpanzees. In patients without hepatitis B virus or acute hepatitis A virus serological markers, non-A, non-B-like nuclear particles were seen in hepatocytes in 28 of 31 cases of presumed non-A, non-B hepatitis, but also in 11 of 12 cases of liver disease not usually attributed to hepatitis viruses. They were also seen in 22 of 24 patients with HBsAg, in 3 of 3 patients with anti-HBc and no HBsAg, in 1 of 2 patients with hepatitis A, in a case of cytomegalovirus hepatitis, and in 16 of 19 patients whose serology was not available or inconclusive.

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