We examined effects of diabetes mellitus (DM) on the pupillary light reflex (PLR). Phasic pupillary response to a single light stimulus (200 ms) (pPLR) and to continuous sinusoidal stimuli with four different frequencies (0.1, 0.
View Article and Find Full Text PDFThe sodium dicarboxylate cotransporter located at the basolateral side supplies renal proximal tubule cells with Krebs cycle intermediates and maintains the driving force for the exchange of organic anions like PAH against alpha-ketoglutarate through the organic anion transporter-1. Recently, we cloned sodium dicarboxylate cotransporter-3 from winter flounder kidney (fNaDC-3). To understand the regulation of fNaDC-3, we preincubated fNaDC-3-expressing oocytes with PMA, a PKC activator.
View Article and Find Full Text PDFAim: To examine effects of diabetes mellitus on the pupillary light reflex it was analysed using a new compact integrated infrared pupillograph (CIP). PATIENTS AN METHODS: We examined 52 patients with diabetes mellitus and 21 control subjects. The initial pupillary diameter was diminished in the group of the diabetics.
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