[Hereditary prolonged QT interval (Romano-Ward syndrome) in a female patient with non-elective cesarean section].

In the Romano-Ward syndrome, an inherited form of abnormally prolonged QT duration is the matter of concern. The frequency-corrected QTc value in the ECG amounts to more than 0.44 s (upper mean value: 0.

[Unusual faulty placement of an internal jugular catheter].

A catheter had been placed, by the Seldinger technique, into the left internal jugular vein of a 29-year-old man requiring intensive care. Routine radiological check of its position using contrast medium (Conray) revealed its tip to be in the pericardial vein. This malposition is facilitated by the course of the venous system in the region of the left brachiocephalic vein.

Investigation of the butyrophenone tranquilizer azaperone and its main metabolites with the Salmonella/microsome test.

In previous experiments, azaperone was found to be weakly mutagenic, after metabolic activation, in the Ames assay. In this study, we subjected metabolites found in rat and swine to the Salmonella/microsome test. 5 histidine-auxotrophic strains were used.

Investigation, with the Salmonella/microsome test, of psychopharmaceuticals used in meat production.

Azaperone, acepromazine, xylazine and diazepam were tested for mutagenic activity. To screen these veterinary drugs we used the Salmonella/microsome test on 5 histidine-auxotrophic strains, with and without metabolic activation. Azaperone and xylazine were found to be weakly mutagenic.