Aim: To investigate the incidence of sight-threatening diabetic retinopathy in Type 2 diabetes mellitus.
Background: In most countries, yearly or biennial screening intervals for diabetic retinopathy in people with Type 2 diabetes are recommended. Fewer screening sessions reduce the effort required of people with Type 2 diabetes and reduce healthcare costs.
Aim: Although diabetic retinopathy (DR) screening is a basic component of diabetes care, uptake of screening programs is less than optimal. Because attendance rates and reasons for non-attendance in an unselected diabetes population are unknown, this study examines incentives and barriers to attend DR-screening.
Method: Four focus groups provided patient-related themes concerning individual decision-making regarding attendance at DR-screening.
Background: Ingestion of high doses of casein hydrolysate stimulates insulin secretion in healthy subjects and patients with type 2 diabetes. The effects of low doses have not been studied. The aim of this study was to assess the effect of lower doses of a casein hydrolysate on the glucose and insulin responses to an oral glucose tolerance test in patients with type 2 diabetes.
View Article and Find Full Text PDFBackground: The prevalence and severity of chronic kidney disease (CKD) in primary care patients with diabetes or hypertension is unknown.
Aim: To assess the prevalence and severity of CKD in patients with diabetes and hypertension; and identify whether age, sex, diabetes, and hypertension are associated with CKD.
Design Of Study: Cross-sectional survey.
Objectives: To compare the value of transvaginal ultrasonographic measurement of the cervical length versus the Bishop score, prior to induction of labour, in predicting the mode of delivery within four days.
Materials And Methods: This longitudinal study included 110 women (at term, singleton, vertex presentation) in whom induction of labour was performed at 37-42 weeks of gestation. Cervical length on transvaginal ultrasound and the Bishop score were assessed prior to induction according to standard protocol.
Objective: To determine whether the HemoCue haemoglobin value measured in fingertip skin puncture blood corresponds to the reference value measured in venous blood.
Design: Prospective.
Method: In two health centres, patients' blood was first drawn from a fingertip skin puncture and the haemoglobin was measured with the HemoCue method (HemoCue B-Haemoglobin AB photometer, Angelholm, Sweden).
Background: In the Netherlands, preventive child health service (CHS) screening plays an important role in the early detection of congenital, developmental, physical, and mental disorders.
Objective: To obtain insight into the referral patterns of children from CHS to general practitioners and from general practitioners to medical specialists.
Methods: Prospective study over 6 months in a semi-urban area in the Netherlands.
Aliment Pharmacol Ther
March 2008
Background: Some studies have shown that short-term use of proton pump inhibitors decreases the absorption of vitamin B12, but the results of studies into long-term proton pump inhibitor use and vitamin B12 deficiency are inconsistent.
Aim: To investigate whether long-term proton pump inhibitor use is associated with an abnormal vitamin B12 status in elderly individuals.
Methods: One hundred and twenty-five long-term (>3, years) proton pump inhibitor users aged 65, years and above were recruited from general practices.
Aim: Low-grade inflammation plays a pivotal role in atherogenesis in type 2 diabetes. Next to its antithrombotic effects, several lines of evidence demonstrate anti-inflammatory properties of aspirin. We determined the effects of aspirin on inflammation - represented by C-reactive protein (CRP) and interleukin-6 (IL-6) - in type 2 diabetic subjects without cardiovascular disease and assessed differential effects of aspirin 300 mg compared with 100 mg.
View Article and Find Full Text PDFObjectives: This study evaluated myocardial function in relation to high-energy phosphate (HEP) metabolism in asymptomatic patients with uncomplicated type 2 diabetes mellitus using magnetic resonance (MR) techniques.
Background: Myocardial dysfunction may occur in patients with type 2 diabetes mellitus in the absence of coronary artery disease or left ventricular (LV) hypertrophy. The mechanisms underlying this diabetic cardiomyopathy are largely unknown, but may involve altered myocardial energy metabolism.
Scand J Prim Health Care
March 2001
Objective: To study differences in diabetes-related parameters in type 2 diabetic patients treated with the support of a Diabetes Service compared to conventional general practice care.
Design: Parallel clinical trial with randomisation at practice level.
Setting: Fifteen general practices.
Aim: To review the relationship between blood glucose level and mortality in patients with Type 2 diabetes mellitus (DM) as reported in the literature.
Methods: Literature search using Medline Search: January 1966 - April 1998.
Keywords: Diabetes, Non Insulin Dependent, Mortality.