Ecosystem service benefits and costs of deep-sea ecosystem restoration.

Deep-sea ecosystems are facing degradation which could have severe consequences for biodiversity and the livelihoods of coastal populations. Ecosystem restoration as a natural based solution has been regarded as a useful means to recover ecosystems. The study provides a social cost-benefit analysis for a proposed project to restore the Dohrn Canyon cold water corals and the deep-sea ecosystem in the Bay of Naples, Italy.

Values of Importance to Patients With Cardiovascular Disease as a Foundation for eHealth Design and Evaluation: Mixed Methods Study.

Background: eHealth interventions are developed to support and facilitate patients with lifestyle changes and self-care tasks after being diagnosed with a cardiovascular disease (CVD). Creating long-lasting effects on lifestyle change and health outcomes with eHealth interventions is challenging and requires good understanding of patient values.

Objective: The aim of the study was to identify values of importance to patients with CVD to aid in designing a technological lifestyle platform.

Short-Term Hypoxia Dampens Inflammation in vivo via Enhanced Adenosine Release and Adenosine 2B Receptor Stimulation.

Hypoxia and inflammation are closely intertwined phenomena. Critically ill patients often suffer from systemic inflammatory conditions and concurrently experience short-lived hypoxia. We evaluated the effects of short-term hypoxia on systemic inflammation, and show that it potently attenuates pro-inflammatory cytokine responses during murine endotoxemia.

Publisher Correction: MSK1 regulates luminal cell differentiation and metastatic dormancy in ER breast cancer.

In the version of this Article originally published, the boxes framing the two plots in Fig. 1g were misaligned from the axes due to a technical error. This has now been corrected in all versions of the Article.

MSK1 regulates luminal cell differentiation and metastatic dormancy in ER breast cancer.

For many patients with breast cancer, symptomatic bone metastases appear after years of latency. How micrometastatic lesions remain dormant and undetectable before initiating colonization is unclear. Here, we describe a mechanism involved in bone metastatic latency of oestrogen receptor-positive (ER) breast cancer.

Short-term hyperoxia does not exert immunologic effects during experimental murine and human endotoxemia.

Oxygen therapy to maintain tissue oxygenation is one of the cornerstones of critical care. Therefore, hyperoxia is often encountered in critically ill patients. Epidemiologic studies have demonstrated that hyperoxia may affect outcome, although mechanisms are unclear.

The role of spatial information in the preservation of the shrimp nursery function of mangroves: a spatially explicit bio-economic model for the assessment of land use trade-offs.

Conversion to aquaculture affects the provision of important ecosystem services provided by mangrove ecosystems, and this effect depends strongly on the location of the conversion. We introduce in a bio-economic mathematical programming model relevant spatial elements that affect the provision of the nursery habitat service of mangroves: (1) direct or indirect connection of mangroves to watercourses; (2) the spatial allocation of aquaculture ponds; and (3) the presence of non-linear relations between mangrove extent and juvenile recruitment to wild shrimp populations. By tracing out the production possibilities frontier of wild and cultivated shrimp, the model assesses the role of spatial information in the trade-off between aquaculture and the nursery habitat function using spatial elements relevant to our model of a mangrove area in Ca Mau Province, Viet Nam.

Bacterial communities associated with Chenopodium album and Stellaria media seeds from arable soils.

The bacterial community compositions in Chenopodium album and Stellaria media seeds recovered from soil (soil weed seedbank), from bulk soil, and from seeds harvested from plants grown in the same soils were compared. It was hypothesized that bacterial communities in soil weed seedbanks are distinct from the ones present in bulk soils. For that purpose, bacterial polymerase chain reaction denaturing gradient gel electrophoresis (PCR-DGGE) fingerprints, made from DNA extracts of different soils and seed fractions, were analyzed by principal component analysis.

Terrestrial metapopulation dynamics: a nonlinear bioeconomic model analysis.

This paper presents a spatially explicit bioeconomic analysis of species conservation in agricultural areas. Wild species in fragmented agricultural landscapes are best approached as metapopulations consisting of a finite number of local populations. Economic analysis of species conservation in fragmented habitat needs to deal with metapopulation theory and its theoretical implications.