Publications by authors named "Gro Solbakken"
Myotonic dystrophy type 1 is an autosomal dominant, inherited multiorgan disorder that can affect people of all ages. It is the most prevalent inherited muscular disease in adults. Late diagnosis points to limited knowledge among the medical community that symptoms other than typical muscular symptoms can dominate.
View Article and Find Full Text PDFIntroduction: Myotonic dystrophy type 1 (DM1) is an inherited neuromuscular disorder that affects multiple organs. In this study, we investigated symptoms of pain and presence of small and large fiber neuropathy in the juvenile and adult form of DM1.
Method: Twenty genetically verified DM1 patients were included.
Background: Pain is prevalent in myotonic dystrophy 1 (DM1). This study investigated whether CTG repeat size, disease duration, BMI and motor and psychological function were related to pain in adult patients with DM1, and if there were gender differences regarding intensity and location of pain.
Method: Cross-sectional design.
Article Synopsis
- Myotonic Dystrophy 1 (DM1) leads to muscle wasting, affecting not only extremity muscles but also trunk muscles, prompting a study to assess the impact of fat infiltration and muscle size in these trunk muscles compared to healthy individuals.
- Using MRI, researchers measured fat infiltration and muscle size in 20 DM1 patients and compared findings with a matched control group, while also correlating these measures with muscle strength and respiratory function.
- Results showed DM1 patients had significantly higher fat infiltration and smaller muscle size in trunk muscles, which correlated with poorer muscle strength, mobility, balance, and reduced lung function.