[Unilateral hydrocephalus secondary to a brain temporal abscess treated by endoscopic septotomy: a case report].

Hydrocephalus is a rare complication of brain abscess, due to either the mass effect on the ventricular system or to the rupture of the abscess in the ventricles. We report here the case of 44-year-old man who was operated on for a temporal lobe abscess of pulmonary origin who presented 6 weeks later with obstructive hydrocephalus secondary to a likely choroid plexus thrombophlebitis. This patient was treated successfully with an endoscopic septotomy.

Cervicosternotomy as an anterior approach to the upper thoracic and cervicothoracic spinal junction.

Object: The cervicothoracic junction is always a difficult area to approach. When operating on this specific area (for tumor or trauma), the aim is generally to decompress and stabilize the spine. The authors describe an improved median sternotomy method for reaching the anterior aspect of the spine down to T-5.

[Treatment of grade 0 intracranial aneurysms: Retrospective study of 79 cases].

Aim: Without precise international recommendations, despite the advances of the ISUAA study, the superiority of microsurgery or endovascular treatment for unruptured intracranial aneurysm (UIA) over the natural history of this disease has not been proved. In this context, the authors evaluate their experience with the aim of assessing the results and risks of the different therapeutics and comparing them with the natural risk of this disease.

Material And Method: From January 1993 to July 2000, 79 patients harboring 110 UIAs were treated.

Brown-Sequard-type myelopathy due to cervical disc herniation associated with severe carotid stenosis prompting rapid combined corpectomy and carotid endarterectomy under deep anticoagulant therapy.

Background Context: The risk of stroke because of carotid retraction during an anterior cervical spine surgery as well as the risk of bleeding complications after an anterior cervical corpectomy under deep anticoagulation and antiplatelet therapy is a surgical issue poorly addressed in the literature.

Purpose: To describe the feasibility and safety of a simultaneous carotid endarterectomy and anterior corpectomy and fusion under deep anticoagulation in a patient with a cervical spinal cord compression and a severe carotid artery stenosis.

Study Design: Case report.

Targeting adrenomedullin receptors with systemic delivery of neutralizing antibodies inhibits tumor angiogenesis and suppresses growth of human tumor xenografts in mice.

Adrenomedullin (AM) is a multifunctional peptide vasodilator that transduces its effects through calcitonin receptor-like receptor/receptor activity modifying protein-2 and -3 (CLR/RAMP2 and CLR/RAMP3). Previously, we reported on the development of an anti-AM antibody that potently inhibits tumor cell proliferation in vitro and tumor growth in vivo. Here, we report the effect of anti-AM receptor antibodies (alphaAMRs) on angiogenesis and tumor growth.

Management of large vestibular schwannomas by combined surgical resection and gamma knife radiosurgery.

In this report, we evaluated the treatment results of a combination of surgery and radiosurgery for large vestibular schwannomas. The series of 8 patients included in this study underwent surgery followed by radiosurgical treatment between January 2000 and January 2006. The patients included 5 males and 3 females aged 24-78 years (mean age: 53 years).

[Prognostic implications of biologic markers in intracranial meningiomas: 120 cases].

Unlabelled: The recurrence and progression of treated intracranial meningiomas highlights the problem of the type of follow-up that should be used and whether early complementary treatment is indicated. The aim of this study was to evaluate different biochemical markers involved in cell proliferation and transformation to identify new prognostic factors in intracranial meningiomas. Between 1989 and 2003, 120 intracranial meningiomas were studied biochemically.

[Value of relative cerebral blood volume measurement using perfusion MRI in glioma management].

Introduction: Neoangiogenesis is a critical feature that can differentiate high-grade from low-grade glioma. Conventional MR imaging does not assess this histological feature accurately. The goal of this study was to evaluate the gain in relative cerebral blood volume measurement using perfusion MRI in the management of cerebral gliomas.

[Intramedullary spinal tuberculoma: report of one case].

Neurological symptoms of tuberculosis are rare, even if there this pathology has been on the rise for a number of years because of HIV. Intramedullary tuberculoma is an exceptional location. We report the case of a patient with no HIV or immunodepression symptoms with intramedullary tuberculoma, revealed by a clinical presentation of insidious onset of myelopathy.

[Minimally invasive transmuscular approach for the treatment of lumbar far lateral disc herniation].

Background: The purpose of this study was to evaluate a minimally invasive surgical technique for the treatment of lumbar far lateral disc herniation. This technique combines the tubular retractor with the operative microscope.

Objective And Methods: This retrospective study analyzed the files of 26 patients: 15 men and 11 women.

[Disappearance of retro-odontoid pseudotumor after C1-C2 transarticular fixation screw].

Atlantoaxial degenerative articular cysts are described in various situations like rheumatoid arthritis, dialysis, and fractures...

Successful treatment of a giant isolated cerebral mucormycotic (zygomycotic) abscess using endoscopic debridement: case report and therapeutic considerations.

Background: Cerebral mucormycosis without rhino-orbital or systemic involvement is an extremely rare condition mostly associated with parenteral drug abuse.

Case Description: We report the case of a 42-year-old woman who presented with hemiparesis of the left side and altered mental status. Neuroradiologic workup demonstrated an inflammatory lesion involving the right basal ganglia.

[Percutaneous pedicle screw fixation and kyphoplasty for management of thoracolumbar burst fractures].

Objective: To evaluate outcome and potential advantages of a percutaneous posterior approach to burst fractures of the thoraco-lumbar junction without neurological complications by means of a technique combining balloon kyphoplasty and percutaneous pedicule screw fixation.

Methods: In this preliminary study patients who suffered traumatic of the thoraco-lumbar junction presented a Magerl type A3 fracture. The mean age of the patients was 64 years (54-78 years).

[Open kyphoplasty for management of metastatic spine fracture].

Introduction: Metastatic spine fractures are very frequent, often occurring in patients with severe medical conditions. Open kyphoplasty and vertebroplasty are part of the classic management of this of fracture. In certain conditions such as spinal cord compression caused by epidural metastatic cancer or collapse of the vertebral body implying a local kyphosis, surgery should allow decompression of the spinal cord and stabilisation of the spine in a simple act.

Spinal Langerhans' cell histiocytosis in a young adult: case report and therapeutic considerations.

We report an unusual case of spinal Langerhans' cell histiocytosis of the cervicothoracic junction in a young adult man. A 17-year-old male was referred to our institution with a 3-week history of cervicothoracic pain associated to a weakness of his right upper limb. Computed tomography and magnetic resonance imaging showed a collapsed T1 vertebral body with epidural soft tissue showing mass effect on spinal cord.

Solitary fibrous tumors of the central nervous system: clinicopathological and therapeutic considerations of 18 cases.

Objective: This is a retrospective study of 18 patients harboring a solitary fibrous tumor of the central nervous system. Therapeutic management and outcome were analyzed.

Methods: Between 1999 and 2004, 18 patients harboring central nervous system solitary fibrous tumors were surgically treated at our two institutions.

Open kyphoplasty for management of metastatic and severe osteoporotic spinal fracture. Technical note.

Object: Elderly patients in poor general health frequently suffer vertebral body (VB) fractures due to osteoporosis or vertebral metastatic lesions. Kyphoplasty and vertebroplasty have become the standard treatment for these types of fractures. In certain conditions that cause local kyphosis, such as spinal cord compression due to a metastatic epidural tumor or the shortening of the spinal canal secondary to vertebral compression, the surgical treatment should provide decompression and stabilization during a short intervention.

[Endovascular treatment of idiopathic intracranial hypertension. Analysis of eight consecutive patients].

Introduction: Optic nerve sheath fenestration or ventricular shunting are classically proposed after failure of medical treatment. Idiopathic intracranial hypertension is caused by venous sinus obstruction in an unknown percentage of cases. Recently, endoluminal venous sinus stenting was proposed as an alternative treatment.

[The value of dynamic cervical MRI in management of selected patients presenting traumatic cervical cord injury].

Objective: The purpose of this report is to describe our experience with dynamic cervical MRI for detection of cervical spinal cord instability in patients presenting spinal cord trauma without fracture or dislocation of the spinal column.

Material And Methods: Since January 2000 a total of 95 patients presenting spinal cord trauma have been treated in our department. All patients underwent MRI for diagnostic work-up.

[Operative treatment of complex lombosacral fracture dislocation: L5 chance fracture with trans S1-S2 dislocation].

Sacral fractures are uncommon injuries that are often diagnosed late, the transverse fracture dislocation of the sacrum at the S1-S2 level associated with a L5 Chance fracture has never been reported. The purpose of this report is to describe operative treatment of transverse fracture dislocation of the sacrum at the S1-S2 level associated with a L5 Chance fracture. A 17-year-old woman sustained multiple injuries in a road accident and presented with hypovolumic shock.

[Idiopathic acute obstructive hydrocephalus. Case report].

Acute hydrocephalus is rarely encountered in adults without venticuloperitoneal or venticuloatrial shunts. The purpose of this report is to describe a case of acute hydrocephalus due to no identifiable cause. A 40-year-old man developed a typical clinical picture of intracranial hypertension within a 24-hours period.

[Transsacral approach to lumbosacral extraforaminal disc herniations].

Introduction: The lateral approach is classically used for surgical treatment of extraforminal disc herniations (EDH). However, its use at the level of the L5-S1 space can require more or less extensive resection of the facet joint. This study reports our experience in the treatment of L5-S1 EDH using the transsacral approach described by Muller and Reulen in 1998.