[The use of cephmetazon in treating infectious inflammatory diseases of the upper and lower urinary tract].

A clinical trial of cephmethasone (Sankyo, Japan) has been performed in 40 patients with pyelonephritis. 3 patients with chronic cystitis. 19 patients with chronic prostatitis.

[The efficacy of bacteriophage preparations in treating inflammatory urologic diseases].

Urinary infection is the most commonly encountered hospital infection. Antibacterial therapy promotes selection and dissemination of polyresistant microorganism strains, development of intestinal dysbacteriosis, reduction of intestinal contamination resistance. Clinical and bacteriological efficacy of urinary infection treatment with bacteriophage preparations (pyocyanic, proteus, staphylococcal, coliphage, combined pyobacteriophage) was studied.

[The conditions for performing extracorporeal lithotripsy with different physicochemical compositions of the urinary stones].

Remote impulse lithotripsy (RIL) parameters were assessed when crushing uroliths with the use of URAT-II lithotriptor. The results were referred to the concrement size, location and physicochemical properties. A total of 365 examinations were made.

[The determination of the chemiluminescence of stimulated blood leukocytes in assessing the activity of chronic pyelonephritis].

The activity of oxidant metabolism was studied in leukocytes from the whole blood of 23 patients diagnosed to have urolithiasis, chronic pyelonephritis in remission. Leukocyte function was evaluated by registration of luminol-dependent chemiluminescence. Barium sulfate microcrystals served leukocyte stimulator.

[The clinical efficacy of the new drug agent ligentén in urology patients].

A clinical trial was made of a new gel ligenten intended for local urethral anesthesia and treatment of infection and inflammation in the lower urinary tracts. Ligenten was given to 52 patients to manage bladder, prostate, urethral infection and inflammation, for local prophylaxis before cystoscopy, urethral bouginage and transurethral surgery. Apparent advantages of intraurethral introduction of the analgetic compared to instrument lubrication are demonstrated.

[The efficacy of Ligenten gel in the prevention and treatment of infectious-inflammatory diseases of the urogenital organs].

A new therapeutic in the form of a gel named ligenten was studied. The gel active components are lidocain, gentamicin and ethonium. Ligenten was shown to have a marked local anesthetic action when administered transurethrally.

[Urinary enzymes induced in rats by intensive physical loading and the effect of the antioxidant potassium fenozan].

The rats subjected to repeated heavy exercises (swimming with the load equal to 10% of body weight) had an increased activity of gamma-glutamyl transpeptidase in the urine. Both the percentage of the rats with hyperenzymuria and the level of enzyme were the highest after the fifth swimming. Water-soluble antioxidant (potassium fenozan) administered intraperitoneally 30 minutes before the swimming abolished the increase of enzymuria and maintained the enzyme activity to the normal level.

[Determination of the composition of the concretions in patients with nephrolithiasis by metabolic indices].

The authors considered an important problem of in vivo verification of urolith composition as specifying the choice of drug treatment and prevention of urolithiasis. 84 nephrolithiasis patients were allocated to 4 groups according to their concrement compositions (after spontaneous or surgical removal): 23 patients with urate calculus, 19 with oxalate, 20 with phosphate and 22 with oxalate-phosphate concrements. Polarizing microscopy, x-ray structural analysis and infrared spectrophotometry were employed for verification of calculi composition.