Publications by authors named "Grisha Weintraub"
Originally developed to meet the challenges of genomic data deluge, GeniePool emerged as a pioneering platform, enabling efficient storage, accessibility, and analysis of vast genomic datasets, enabled due to its data lake architecture. Building on this foundation, GeniePool 2.0 advances genomic analysis through the integration of cutting-edge variant databases, such as CHM13-T2T, AlphaMissense, and gnomAD V4, coupled with the capability for variant co-occurrence queries.
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- There's a growing need for combining genomic data with phenotypic information, but existing databases aren't user-friendly for accessing this combined data.
- GeniePool was developed to simplify access to thousands of next-generation sequencing (NGS) samples by continuously downloading and preprocessing data from the Sequence Read Archive (SRA).
- This new tool offers a user-friendly web service and API, enabling clinicians and researchers to easily query NGS data and related study information, enhancing current database functionalities.