Discrimination between keratoconus, forme fruste keratoconus, and normal eyes using a novel OCT-based tomographer.

Purpose: To combine objective machine-derived corneal parameters obtained with new swept-source optical coherence tomography (SS-OCT) tomographer (Anterion) to differentiate between normal (N), keratoconus (KC) and forme fruste KC (FFKC).

Setting: Laser Center, Hôpital Fondation Adolphe de Rothschild, Paris, France.

Design: Retrospective study.

Intraocular Pressure Changes After Intravitreal Fluocinolone Acetonide Implant: Results from Four European Countries.

Introduction: The 0.19 mg fluocinolone acetonide (FAc) intravitreal implant delivers a continuous intravitreal corticosteroid dose for the treatment of refractory diabetic macular oedema (DMO). The aim of this study was to assess the impact of an FAc intravitreal implant on intraocular pressure (IOP).

Antirheumatic Drug Intake Influence on Occurrence of COVID-19 Infection in Ambulatory Patients with Immune-Mediated Inflammatory Diseases: A Cohort Study.

Introduction: We aimed to study the prevalence of a history of COVID-19 infection among patients suffering from systemic lupus erythematosus (SLE), rheumatoid arthritis (RA), Sjögren's syndrome (SjS) or psoriatic arthritis (PsA), and the potential influence of long-term hydroxychloroquine (HCQ) intake.

Methods: We performed an observational monocentric cohort study at the Adolphe de Rothschild Foundation Hospital ophthalmology division (Paris, France). Electronic medical records (EMR) data were searched for keywords associated with SLE, RA, SjS, or PsA.

Outcomes of Gel Stent Implantation for Glaucoma in Patients With Previous Corneal Graft Surgery: A Case Series.

Purpose: To report a series of 5 cases with successful placement of a minimally invasive glaucoma surgery (MIGS) device for glaucoma refractory to medical management in patients with previous corneal grafts.

Methods: This is a retrospective analysis of all cases with a Xen45 Gel Stent (Allergan plc, Dublin, Ireland) for ocular hypertension and glaucoma refractory to medical treatment after corneal graft surgery between 2016 and 2019 at the Rothschild Foundation, Paris. We did the imaging studies and studied the intraocular pressure (IOP) and the endothelial cell count preimplantation and postimplantation with a MIGS device.

Comparison of Laser Platform Estimation and Objective Measurement of Maximum Ablation Depth Using Scheimpflug Pachymetry in Myopic Femtosecond Laser In Situ Keratomileusis.

Purpose: To compare the preoperative estimation of maximum ablation depth provided by the laser platform with objective measurement using Scheimpflug pachymetry in myopic femtosecond laser-assisted in situ keratomileusis (FS-LASIK).

Methods: This is a prospective study carried out at the Rothschild Foundation, Paris, France. In 89 consecutive myopic eyes (45 patients) treated with FS-LASIK, the maximum ablation depth was calculated by measuring the difference between preoperative and 3-month postoperative measurements in central corneal thickness using Scheimpflug pachymetry (Pentacam HR; Oculus Optikgeräte, Wetzlar, Germany).

Recurrent Exposure of XEN Gel Stent Implant and Conjunctival Erosion.

Purpose: The purpose of this study was to report a case of recurrent conjunctival erosion and XEN Gel Stent exposure after implantation in a primary open-angle glaucoma patient. Minimally invasive glaucoma surgery (MIGS) is a new approach in glaucoma surgery, and there is a lack of published data with regard to the management of postoperative ocular surface complications.

Methods: This is a case report of a patient with a persistent corneal erosion after XEN Gel Stent implantation.

Changes to Corneal Aberrations and Vision After Monovision in Patients With Hyperopia After Using a Customized Aspheric Ablation Profile to Increase Corneal Asphericity (Q-factor).

Purpose: To evaluate the visual outcomes and fourth-order Zernike spherical aberrations induced with a customized change in corneal asphericity (ΔQ) correction of presbyopia combined with monovision for hyperopic patients.

Methods: Consecutive hyperopic patients who underwent presbyopic LASIK between September 2013 and July 2014 were included. For the non-dominant eyes, the aspheric ablation profile associated with a myopic refraction was planned using the Custom-Q nomogram (Alcon Laboratories, Inc.

Repeatability of Keratometry Measurements Obtained With Three Topographers in Keratoconic and Normal Corneas.

Purpose: To assess the repeatability of the corneal topography functions of Orbscan II (Bausch & Lomb, Rochester, NY), OPD-Scan III (Nidek, Gamagori, Japan), and iTrace (Tracey Technologies, Houston, TX) in keratoconic eyes and in a control group of normal patients.

Methods: In this prospective cohort study, patients were recruited between November 2011 and May 2012. Measurements were performed with a combined Placido-scanning slit system (Orbscan II) and two combined Placido-aberrometer systems (OPD-Scan III and iTrace).

Opaque Bubble Layer Risk Factors in Femtosecond Laser-assisted LASIK.

Purpose: To determine the characteristics and risk factors for occurrence of opaque bubble layer (OBL) during femtosecond laser-assisted flap creation for LASIK.

Methods: One hundred ninety-eight eyes of 102 consecutive patients who underwent LASIK flap creation performed with the Alcon WaveLight FS200 laser (Alcon Laboratories, Inc., Fort Worth, TX) were retrospectively analyzed in a cohort study.

Intraoperative OCT-Assisted DMEK: 14 Consecutive Cases.

Purpose: To describe the utility of a new intraoperative optical coherence tomographer (OCT) to evaluate endothelio-Descemet graft orientation during Descemet membrane endothelial keratoplasty (DMEK) procedures.

Methods: Prospective, observational, and single-center pilot case series including 14 eyes of 14 patients consecutively scheduled for DMEK surgery. After injecting the graft into the anterior chamber, the graft orientation was assessed with the help of anterior segment OCT.

Objective assessment of crystalline lens opacity level by measuring ocular light scattering with a double-pass system.

Purpose: To assess the crystalline lens opacity level by measuring ocular light scattering with a double-pass system.

Design: Prospective, single-center, cross-sectional study.

Methods: Two hundred fifty-three eyes of 135 patients referred for cataract evaluation were enrolled.

Corneal thickness, curvature, and elevation readings in normal corneas: combined Placido-Scheimpflug system versus combined Placido-scanning-slit system.

Purpose: To evaluate agreement in central corneal thickness (CCT), keratometry, and anterior and posterior elevation map measurements in normal corneas between a combined Placido-Scheimpflug system and a combined Placido-scanning-slit elevation topography system.

Setting: Department of Cataract & Refractive Surgery, Rothschild Foundation, Paris, France.

Design: Evaluation of diagnostic test or technology.

Assessment of corneal biomechanical properties in normal tension glaucoma and comparison with open-angle glaucoma, ocular hypertension, and normal eyes.

Purpose: To assess the biomechanical properties of corneas in patients with normal tension glaucoma (NTG) and to compare them with those of patients with primary open-angle glaucoma (POAG), ocular hypertension (OHT), and normal controls (N).

Methods: Corneal hysteresis (CH), corneal resistance factor (CRF), Goldmann intraocular pressure (IOPg), and corneal compensated IOP (IOPcc) were obtained using an ocular response analyzer for 28 eyes in 14 patients with NTG, 75 eyes in 38 patients with chronic POAG, 53 eyes of 27 patients with OHT, and 44 eyes of 22 N controls. IOP using Goldmann applanation tonometry (IOPGA) and ultrasonic central corneal thickness (CCT) were also measured for each eye.

Bilateral loss in the quality of vision associated with anterior corneal protrusion after hyperopic LASIK followed by intrastromal femtolaser-assisted incisions.

A patient was treated bilaterally for hyperopia (twice in the right eye and 3 times in the left eye) using laser in situ keratomileusis (LASIK) and achieved stable vision. Preoperatively, there was no known risk factor for ectasia. Three years after the last LASIK enhancement treatment, intrastromal femtolaser-assisted incisions (Intracor procedure using the Technolas femtosecond laser) were made bilaterally.