Publications by Grigoriy N Poroshin

Publications by authors named "Grigoriy N Poroshin"

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PASylation technology improves recombinant interferon-β1b solubility, stability, and biological activity.

Elizaveta A Zvonova Alexander V Ershov Olga A Ershova Marina A Sudomoina Maksim B Degterev Grigoriy N Poroshin

Appl Microbiol Biotechnol

March 2017

Recombinant interferon-β1b (IFN-β1b) is an effective remedy against multiple sclerosis and other diseases. However, use of small polypeptide (molecular weight is around 18.5 kDa) is limited due to poor solubility, stability, and short half-life in systemic circulation.

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