Polylactide-Meso-Substituted Arylporphyrin Composites: Structure, Properties and Antibacterial Activity.

The structural features and antibacterial properties of polymer-porphyrin composites were investigated. Meso-substituted arylporphyrin 0.2-0.

A New Approach to the Synthesis of Nanocrystalline Cobalt Boride in the Course of the Thermal Decomposition of Cobalt Complexes [Co(DMF)] with Boron Cluster Anions.

In the course of the study, nanocrystalline cobalt monoboride was prepared by thermal decomposition of precursors [Co(DMF)][An], where [An] = [BH] (), [-BH] () or [BCl] () in an argon atmosphere. Three new salt-like compounds - were prepared when Co(NO) was allowed to react with (EtNH)[An]. Compound is new; the structures of compounds and have been previously reported.

Non-Covalent Interactions in the Crystal Structures of Perbrominated Sulfonium Derivatives of the -Decaborate Anion.

A new series of compounds based on perbrominated disubstituted sulfonium derivatives of the -decaborate anion (-BuN)[2-BBrSR] (R = -Pr, -Pr, -Bu, -CH, -CH, -CH) was obtained, characterised by modern physicochemical methods of analysis. According to the results of an X-ray diffraction study, some of the anions and solvate molecules were disordered. The cations (-BuN) and anions [2-BBrSR] were associated via C-H…Br and H…H contacts.

Development of novel darunavir amorphous solid dispersions with mesoporous carriers.

The aim of this work was to compare mesoporous carriers based on silica and magnesium aluminosilicate in the amorphous solid dispersion production. Darunavir has been selected as an active pharmaceutical ingredient that is classified as a Class 2 BCS substance and exists in two commercially available forms: crystalline ethanolate and amorphous. In the course of the study, the conditions for the preparation of amorphous samples with the selected carriers were evaluated within the framework of the most common methods for obtaining solid dispersions - hot-melt extrusion, solvent wetting, and spray drying.