Chemical composition, energy value and 137Cs and 90Sr content in daily diets were assessed in rural population from the region controlled after the Chernobyl accident. As shown by low urine excretion of vitamins (thiamine, ascorbic acid, riboflavin, N1-methylnicotinamide), the population suffer from vitamin deficiency, especially in winter and spring. Levels of the radionuclides rose 1.
View Article and Find Full Text PDFA trial has been performed of a new sweetening agent saccharol, glycosides complex, on energy metabolism in rats with experimental alloxan diabetes. Elevated glucose level observed in rats with insulin insufficiency was associated with hexokinase activity inhibition and changes in the activity of the enzymes involved in glucose-6-phosphate transformation: enhanced activity of glucose-6-phosphatase and glucose-6-phosphate dehydrogenase against inhibition of phosphoglucomutase activity. Introduction of saccharose aggravated the above shifts in the rat liver, whereas saccharol possesses a protective action on hexokinase hepatic reaction and enzymes of glucose-6-phosphate conversion, reduced blood glucose.
View Article and Find Full Text PDFAnimals received saccharol adequate (by sweetness) to sugar, and in 10- and 50-fold increased amounts. The data of chronic 10-month experiments studied in the time course after 2, 5, 10 months have permitted a conclusion that saccharol included into the ration during long periods, does not produce a significant effect on the parameters of metabolic processes and morphological picture of the internal organs in test animals. Saccharol in 50-fold increased amounts inhibits the activity of oxidative phosphorylation in the hepatic tissue of rats.
View Article and Find Full Text PDFThe influence of new exopolysaccharide, synthesized by Candida tropicalis and Pseudomonas sp. consortium in ethanol, on the animal body was studied in chronic experiments conducted in 200 non-inbred white rats. The animals were sacrificed after 3, 10 and 18 months of follow-up.
View Article and Find Full Text PDFFrom the observations on 18 patients and the experiments on 77 dogs with experimental pancreatitis neuro-humoral interrelations and hydrocortisone effect upon the respiratory function have been studied. Both in the clinic and in the experiment the authors have found the intermediate metabolism disturbed: adrenaline-like substances blood level rises, while the cholinergic complex blood level drops dramatically. The conclusion on a vital importance of a consecutive neuro-humoral correction with the use of cholinomimetics and corticosteroids in pancreatitis is drawn.
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