Publications by authors named "Grigor'ev G"

The article highlights the main stages of the development of the Department of Otorhinolaryngology of the Federal state budgetary educational institution of higher education 'Ural State Medical University' since its foundation up to the present time. The principal areas of research and clinical activities of the Department at different periods of its history are presented.

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Pseudomeningocele is an abnormal extradural collection of the cerebrospinal fluid in soft tissues, communicating with the arachnoid space through a dural defect. Postoperative pseudomenigocele of the thoracic spine presenting with myelopathy is a rare phenomenon; we found only two such cases in the literature. A clinical case of a female patient operated on for meningioma at the Th3-Th4 level with postoperative pseudomenigocele and spinal cord compression is presented.

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The study was carried out to determine percentage of hazardous, dangerous and possibly dependent alcohol consumption among physicians of Yakutsk. The relationship between social hygienic aspects accompanying hazardous and dangerous alcohol consumption was analyzed. The risk factors were established.

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A method for physiological hemoglobin elimination from erythrocytes is proposed. Its characteristic feature is increase of erythrocyte membrane permeability and complete release of hemoglobin from erythrocytes by adding an equal volume of 2% papaverin hydrochloride to washed erythrocyte suspension, followed by washing of empty erythrocyte membranes in isotonic sodium chloride solution. Clean intact erythrocytic membranes are obtained, possessing the hemostatic functions typical of blood platelets.

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Clinical and otoneurological examinations were carried out during 35 years in 1176 patients with various vestibular disorders. Positional nystagmus (PN) was found in 478 patients (40.4%).

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[Positioning nystagmus].

Vestn Otorinolaringol

September 1996

256 patients with postural vertigo were examined clinically and neurootologically. Positioning nystagmus (PN) was detected in 209 (81.6%) of them.

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The possibilities of the new chromatomembrane method in the removal of oxygen dissolved in water are studied. The scheme of the water deoxygenation process is determined. The new reagent-free method allows production of water with oxygen content at the level of a few ppb.

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The conception on fungal origin of sergentella-like elements in peripheral blood proposed by A. N. Dekhkan-Khodzhaeva et al.

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Total number of red blood cells, their acid resistance, deformability and fragmentation were studied in rats after intramuscular injection of a semilethal dose of viper poison. It was shown that most significant changes in the above parameters took place 120 min after the poison administration: diminution of red blood cell number, disappearance of high-resistant red blood cells, increase of fragmentary cell number, lowering of deformability.

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The problem of otogenic intracranial complications is very important for medical practice. This paper presents data on the incidence, clinical development and outcome of intracranial complications of purulent otitis media. During 1979-1988 the ENT Department of the City First Aid Hospital treated 82 patients with otogenic intracranial complications, which developed often in the case of acute than chronic otitis media.

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In experiments in vitro it has been established that heparin does not have a direct hemolyzing action, but it significantly reduces red blood cell resistance to acid. In experiments in vivo heparin significantly intensifies red blood cell resistance to the action of acid hemolytics. Hemolysis during intoxication with the toxins studied is, to a greater extent, secondary in relation to the intravascular blood coagulation.

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In this article a practical case is described when gunshot directions and position of a victim's body at the moment of each shot were determined by natural simulation using an LG-78 laser (made in the form of a gun).

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An antiarrhythmic effect of lithium oxybutyrate was demonstrated in 81% of patients with ventricular extrasystole in the presence of affective disturbances, those with hypersympathicotonus in particular. In arrhythmic cases, lithium oxybutyrate was shown to have a hypokinetic effect on central hemodynamics and contribute to peripheral vasodilatation without causing clinically apparent circulatory disorders. The drug inhibits platelet aggregation and moderately increases blood procoagulation activity in the presence of greater erythrocyte deformability and improved bulbar conjunctival microcirculation.

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Effects of ethmozine and ritmilen were studied in 75 patients with different disorders of cardiac rhythm predominantly proceeding in the form of extrasystole arrhythmia. The drugs were found to exert a distinct antiaggregant action on platelets and erythrocytes which was particularly pronounced at intravenous administration and transiently increased the number of leukocytes and their aggregation. A decrease of platelet aggregation was accompanied by an increase of their number and rejuvenascence of thrombocytogram.

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Alterations in membrane proteins of erythrocytes were studied by means of polyacrylamide gel electrophoresis in presence of sodium dodecylsulphate during maturation of the blood cells in an organism, in long-term storage of blood and under conditions of incubation of the erythrocyte shadows in autoplasm. Under the conditions studied the main membrane polypeptides of erythrocytes were shown to be stable. At the same time, maturation of erythrocytes was accompanied by quantitative alterations in some peripheric polypeptides due to interconnected reactions loss of some membrane proteins and their absorption from blood plasma.

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