Outpatient CBT for Motor Functional Neurological Disorder and Other Neuropsychiatric Conditions: A Retrospective Case Comparison.

Objective: No gold-standard treatment exists for motor functional neurological disorder (mFND), and limited evidence has been found for the effectiveness of cognitive-behavioral therapy (CBT) in treating the disorder. This study examined sociodemographic and clinical characteristics, treatment outcomes, and treatment dropout among patients with and without mFND who received CBT in a neuropsychiatric outpatient clinic in the United Kingdom.

Methods: Data from a large anonymized psychiatric register were used to identify patients who received outpatient CBT in a neuropsychiatry clinic between 2006 and 2016 and who had either mFND (N=98) or other neuropsychiatric conditions (ONP) (N=76, control group).

Electrochemical Performance of Nanosized Disordered LiVOPO.

ε-LiVOPO is a promising multielectron cathode material for Li-ion batteries that can accommodate two electrons per vanadium, leading to higher energy densities. However, poor electronic conductivity and low lithium ion diffusivity currently result in low rate capability and poor cycle life. To enhance the electrochemical performance of ε-LiVOPO, in this work, we optimized its solid-state synthesis route using in situ synchrotron X-ray diffraction and applied a combination of high-energy ball-milling with electronically and ionically conductive coatings aiming to improve bulk and surface Li diffusion.

Cation Disorder and Lithium Insertion Mechanism of Wadsley-Roth Crystallographic Shear Phases from First Principles.

Wadsley-Roth crystallographic shear phases form a family of compounds that have attracted attention due to their excellent performance as lithium-ion battery electrodes. The complex crystallographic structure of these materials poses a challenge for first-principles computational modeling and hinders the understanding of their structural, electronic and dynamic properties. In this article, we study three different niobium-tungsten oxide crystallographic shear phases (NbWO, NbWO, NbWO) using an enumeration-based approach and first-principles density-functional theory calculations.

Acute reperfusion for ST-elevation myocardial infarction in New Zealand (2015-2017): patient and system delay (ANZACS-QI 29).

Aim: Prompt access to cardiac defibrillation and reperfusion therapy improves outcomes in patients with ST-segment elevation myocardial infarction (STEMI). The study aim was to describe the 'patient' and 'system' delay in patients who receive acute reperfusion therapy for ST-elevation myocardial infarction (STEMI) in New Zealand.

Methods: In 2015-17, 3,857 patients who received acute reperfusion therapy were captured in the All New Zealand Acute Coronary Syndrome Quality Improvement (ANZACS-QI) registry.

Short-range ordering in a battery electrode, the 'cation-disordered' rocksalt LiNbMnO.

Cation order, with a local structure related to γ-LiFeO, is observed in the nominally cation-disordered Li-excess rocksalt LiNbMnOvia X-ray diffraction, neutron pair distribution function analysis, magnetic susceptibility and NMR spectroscopy. The correlation length of ordering depends on synthesis conditions and has implications for the electrochemistry of these phases.

When Do Anisotropic Magnetic Susceptibilities Lead to Large NMR Shifts? Exploring Particle Shape Effects in the Battery Electrode Material LiFePO.

Materials used as electrodes in energy storage devices have been extensively studied with solid-state NMR spectroscopy. Due to the almost ubiquitous presence of transition metals, these systems are also often magnetic. While it is well known that the presence of anisotropic bulk magnetic susceptibility (ABMS) leads to broadening of resonances under magic angle spinning, we show that for monodisperse and nonspherical particle morphologies the ABMS can also lead to considerable shifts, which vary substantially as a function of particle shape.

A O paramagnetic NMR study of SmO, EuO, and Sm/Eu-substituted CeO.

Paramagnetic solid-state NMR of lanthanide (Ln) containing materials can be challenging due to the high electron spin states possible for the Ln f electrons, which result in large paramagnetic shifts, and these difficulties are compounded for O due to the low natural abundance and quadrupolar character. In this work, we present examples of O NMR experiments for lanthanide oxides and strategies to overcome these difficulties. In particular, we record and assign the O NMR spectra of monoclinic SmO and EuO for the first time, as well as performing density functional theory (DFT) calculations to gain further insight into the spectra.

Paramagnetic NMR in solution and the solid state.

The field of paramagnetic NMR has expanded considerably in recent years. This review addresses both the theoretical description of paramagnetic NMR, and the way in which it is currently practised. We provide a review of the theory of the NMR parameters of systems in both solution and the solid state.

Mouse ANKRD31 Regulates Spatiotemporal Patterning of Meiotic Recombination Initiation and Ensures Recombination between X and Y Sex Chromosomes.

Orderly segregation of chromosomes during meiosis requires that crossovers form between homologous chromosomes by recombination. Programmed DNA double-strand breaks (DSBs) initiate meiotic recombination. We identify ANKRD31 as a key component of complexes of DSB-promoting proteins that assemble on meiotic chromosome axes.

The contribution of avoidable mortality to the life expectancy gap in Māori and Pacific populations in New Zealand-a decomposition analysis.

Aim: To determine the contribution of avoidable causes of death to the life expectancy differentials in both Māori and Pacific compared with non-Māori/non-Pacific ethnic groups in New Zealand.

Methods: Death registration data and population data for New Zealand between 2013-15 was used to calculate life expectancy. A recent definition of avoidable mortality was used to identify potentially avoidable deaths.

High level of capture of coronary intervention and associated acute coronary syndromes in the all New Zealand acute coronary syndrome quality improvement cardiac registry and excellent agreement with national administrative datasets (ANZACS-QI 25).

Background: The All New Zealand Acute Coronary Syndrome Quality Improvement (ANZACS-QI) registry was designed to collect data on all coronary angiograms and percutaneous coronary interventions (PCI) in New Zealand, and all acute coronary syndromes (ACS) associated with these procedures. This study compares the completeness of capture in ANZACS-QI of coronary procedures and ACS admissions with those recorded in the National Hospitalisation Dataset and evaluates data quality by assessing agreement in ACS diagnoses and coronary procedures between datasets.

Methods: The national dataset, which included all New Zealand public hospital admissions in 2015 (n=962,700 episodes), was anonymously linked with the ANZACS-QI CathPCI (n=14,649 coronary angiogram episodes) and ACS cohorts (n=8,141 episodes) for 2015.

Relationship between estimated glomerular filtration rate and incident cardiovascular disease in an ethnically diverse primary care cohort.

Aim: To investigate eGFR as an independent risk factor for CVD in a New Zealand primary care cohort, stratified by disease status (prior CVD, diabetes or no CVD or diabetes).

Method: The PREDICT-CVD open cohort study is a large, ethnically diverse, New Zealand primary care cohort, generated by using a web-based CVD risk assessment tool. Using encrypted identifiers, participant profiles were linked anonymously to a regional laboratory database (to determine renal function) and to national hospitalisation and mortality datasets.

Predicting Bleeding Risk to Guide Aspirin Use for the Primary Prevention of Cardiovascular Disease: A Cohort Study.

Background: Many prognostic models for cardiovascular risk can be used to estimate aspirin's absolute benefits, but few bleeding risk models are available to estimate its likely harms.

Objective: To develop prognostic bleeding risk models among persons in whom aspirin might be considered for the primary prevention of cardiovascular disease (CVD).

Design: Prospective cohort study.

Layered CeSO and LiCeSO Oxide Chalcogenides Obtained via Topotactic Oxidative and Reductive Transformations.

The chemical accessibility of the Ce oxidation state enables redox chemistry to be performed on the naturally coinage-metal-deficient phases CeMSO (M = Cu, Ag). A metastable black compound with the PbFCl structure type (space group P4/ nmm: a = 3.8396(1) Å, c = 6.

Strongly coloured thiocyanate frameworks with perovskite-analogue structures.

We report the first examples of thiocyanate-based analogues of the cyanide Prussian blue compounds, M[Bi(SCN)], M = Fe, Cr, Sc. These compounds adopt the primitive cubic topology and show strict cation order. Optical absorption measurements show these compounds have band gaps within the visible and near IR region, suggesting that they may be useful for applications where light harvesting is key, such as photocatalysis.

Three-dimensional pulsed field gradient NMR measurements of self-diffusion in anisotropic materials for energy storage applications.

Anisotropic battery electrodes that allow enhanced diffusion through the thickness of the electrode can be engineered to improve the rate performance, but direct measurement of 3D diffusion in this pore structure is extremely challenging. To address this, we used 1H and 7Li pulsed field gradient (PFG) NMR to measure anisotropic diffusion in a model porous silicon substrate. We show that NMR spectroscopy can resolve solvent molecules and ions (here, in H2O, DMSO, and the battery electrolyte LIPF6:DC:EMC) in and outside of the pores of the Si substrate, allowing the diffusion coefficients of the ion/molecules in the two components to be individually determined.

Fluorine-free water-in-ionomer electrolytes for sustainable lithium-ion batteries.

The continuously increasing number and size of lithium-based batteries developed for large-scale applications raise serious environmental concerns. Herein, we address the issues related to electrolyte toxicity and safety by proposing a "water-in-ionomer" type of electrolyte which replaces organic solvents by water and expensive and toxic fluorinated lithium salts by a non-fluorinated, inexpensive and non-toxic superabsorbing ionomer, lithium polyacrylate. Interestingly, the electrochemical stability window of this electrolyte is extended greatly, even for high water contents.

The Role of Ionic Liquid Breakdown in the Electrochemical Metallization of VO: An NMR Study of Gating Mechanisms and VO Reduction.

Metallization of initially insulating VO via ionic liquid electrolytes, otherwise known as electrolyte gating, has recently been a topic of much interest for possible applications such as Mott transistors and memory devices. It is clear that the metallization takes place electrochemically, and, in particular, there has previously been extensive evidence for the removal of small amounts of oxygen during ionic liquid gating. Hydrogen intercalation has also been proposed, but the source of the hydrogen has remained unclear.

Correction: Synthesis of Ca(PF), formed via nitrosonium oxidation of calcium.

Correction for 'Synthesis of Ca(PF), formed via nitrosonium oxidation of calcium' by Evan N. Keyzer et al., Chem.

Health and mass unemployment events-developing a framework for preparedness and response.

Background: Mass unemployment events are not uncommon yet the impact on health is not well recognised. There is a need for a preparedness and response framework, as exists for other events that threaten population health.

Methods: Framework informed by a narrative review of the impact of mass unemployment on health (studies published in English from 1990 to 2016), and qualitative data from 23 semi-structured interviews with individuals connected to historical national and international events, addressing gaps in published literature on lessons learnt from past responses.

PRDM9, a driver of the genetic map.

During meiosis, maternal and paternal chromosomes undergo exchanges by homologous recombination. This is essential for fertility and contributes to genome evolution. In many eukaryotes, sites of meiotic recombination, also called hotspots, are regions of accessible chromatin, but in many vertebrates, their location follows a distinct pattern and is specified by PR domain-containing protein 9 (PRDM9).

Data on saponins, xylan and cellulose yield obtained from quinoa stalks after pressurized hot water extraction.

The data we present below are linked to our research paper "Integrated process for sequential extraction of saponins, xylan and cellulose from quinoa stalks ( Willd.)" (Gil-Ramírez et al., 2018) [1].

Niobium tungsten oxides for high-rate lithium-ion energy storage.

The maximum power output and minimum charging time of a lithium-ion battery depend on both ionic and electronic transport. Ionic diffusion within the electrochemically active particles generally represents a fundamental limitation to the rate at which a battery can be charged and discharged. To compensate for the relatively slow solid-state ionic diffusion and to enable high power and rapid charging, the active particles are frequently reduced to nanometre dimensions, to the detriment of volumetric packing density, cost, stability and sustainability.