Publications by authors named "Grete Monsen"
Article Synopsis
- Regular measurement of prothrombin time (PT) as an international normalized ratio (INR) is crucial for the safe use of warfarin, and the microINR portable coagulometer was evaluated by SKUP for this purpose.
- The study involved 186 patients and compared results from a standard laboratory method to the microINR device, revealing an imprecision of 6% for INR values ≥2.5 and meeting accuracy standards, but not the imprecision requirement.
- User-friendliness of the device's manual was rated as intermediate, while operating conditions were deemed unsatisfactory, but time efficiency was considered satisfactory.
Background: Biological variation is usually estimated in healthy individuals during steady-state conditions. The aim of this study was to estimate the in-treatment biological variation of the International normalised ratio (INR) and to investigate to what extent the different levels of coagulation factors could explain this variation.
Methods: Blood samples were collected from randomly included patients on warfarin treatment.
Background: The reasons for discrepancies between International Normalized Ratio (INR) results determined by point-of-care-instruments and laboratory measurements are not fully understood. In this study we investigated whether different levels of coagulation factors in the plasma of patients can explain some of the systematic and/or random parts of the difference in INR between the instruments.
Methods: Blood samples were collected at four different patient visits from each of 34 outpatients on warfarin treatment.
Background: Observed differences between results obtained from comparison of instruments used to measure international normalized ratio (INR) have been higher than expected from the imprecision of the instruments. In this study the variation of these differences was divided into subcomponents, and each of the subcomponents was estimated.
Methods: Blood samples were collected at 4 different patient visits from each of 36 outpatients who were receiving warfarin treatment and were included in the study.
Standardized evaluation of nine instruments for self-monitoring of blood glucose.
Diabetes Technol Ther
December 2008
Background: Instruments for self-monitoring of blood glucose (SMBG) should undergo a standardized evaluation including a user-test before being marketed. In this study the results from standardized evaluations of nine different SMBG instruments are presented, and the standardized evaluation is discussed.
Methods: Approximately 80 diabetes patients using three lots of test strips participated in each evaluation.