Publications by authors named "Grekova A"

Article Synopsis
  • * Traditional methods for inferring regulatory networks struggle with missing data, but recent advancements in sparse regression models show promise, although they haven't been widely used in this context yet.
  • * By integrating these advanced regression techniques into KiMONo, a multi-omics network inference approach, the study demonstrates that handling missing data effectively can improve the accuracy of network inference, allowing researchers to make better use of incomplete multi-omics data.
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We report the geometry, kinetic energy, and some optical properties of the 6,6,12-graphyne-based systems. We obtained the values of their binding energies and structural characteristics such as bond lengths and valence angles. Moreover, using nonorthogonal tight-binding molecular dynamics, we carried out a comparative analysis of the thermal stability of 6,6,12-graphyne-based isolated fragments (oligomer) and two-dimensional crystals constructed on its basis in a wide temperature range from 2500 to 4000 K.

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SAPO-34 nanocrystals with sizes of 50-150 nm were obtained via steam-assisted crystallization (SAC) for 5 h at 200 °C from two types of aluminum precursors-aluminum isopropoxide and boehmite. A reaction mixture composition with a small amount of organic template tetraehylammonium hydroxide (TEAOH) was used with the molar ratio TEAOH/AlO = 1/1. The alumina precursor type and duration of the SAC (5 and 24 h) on the crystal size, texture, and acid properties were investigated.

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Aim: An analysis of coronavirus infection in Russia and evaluation of different AVT regimens effectiveness.

Materials And Methods: The study involved a retrospective analysis of 1082 patient records with laboratory-confirmed COVID-19 in 17 regions of Russia. The number of men and women was equal, mean age 48.

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Aim: To identify the features of thinking of young people, whose mental development was carried out in conditions of life virtualization (in a networked society).

Material And Methods: The study included 310 mentally healthy respondents, aged from 18 to 20 years, who study in universities of St. Petersburg.

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Aim: The aim of the study is to obtain additional data on safety and therapeutic efficacy of the antiviral drug Arbidol (umifenovir) in patients with a diagnosis of influenza and common cold.

Materials And Methods: Double-blind, randomized, placebo-controlled clinical study investigating efficacy and safety of Arbidol (umifenovir) in Treatment and Prophylaxis of Influenza and Common Cold (ARBITR) IV phase started in November 2011 and completed in April 2016 on the basis of 15 research centers in various regions of the Russian Federation. A total of 359 patients, aged 18 to 65 years with influenza or acute respiratory tract infection, of no more than 36 hours' duration were enrolled in the study.

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Aim: To identify risk factors (RFs) for the development of bacterial complications and the prolonged course of influenza and other acute respiratory viral infections (ARVIs) among inpatients treated in Russian healthcare facilities in the post-pandemic period; to determine the clinical presentation of the disease (flu-like syndrome) in risk-group people and to evaluate the efficacy of antiviral therapy with arbidol (umifenovir).

Material And Methods: The investigators retrospectively analyzed randomly selected medical records of inpatients with influenza and other ARVI in 88 hospitals from 50 regions of the Russian Federation: those of 3532 and 1755 patients in the 2010-2011 and 2014-2015 seasons, respectively, by applying parametric and nonparametric statistical methods.

Results: The built database of patients with influenza-like syndrome contained data from the histories of 2072 men and 2537 women, of whom there were 317 (12.

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The emotional-painful stress causes a more pronounced decrease in affinity of hemoglobin to oxygen in portal blood compared with mixed blood. This contributes to increased oxygen pressure in hepatocytes and activates free radical processes in liver microsomes. Activation of lipid peroxidation is accompanied by changes in physical properties (microviscosity, polarity) of microsomal membranes.

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The authors give some data on restitutional therapy of 516 patients (400 with sequelae following strokes and 116 with transient disorders of cerebral circulation). Treatment of the first group was made in a neurological ward, the second--in a cardiological sanatorium. The programme of restitutional therapy provided the use of psychosocial and biological methods, an appeal to the personality and stage-by-stage accomplishment of rehabilitative measures.

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