Publications by authors named "Gregory R De Meyer"
Article Synopsis
- The study investigated sarcopenia (muscle loss) in COVID-19 patients in intensive care by using ultrasound to measure muscle properties over time.
- Results showed that changes in muscle thickness of the diaphragm and quadriceps (rectus femoris) were important for patient survival, with stable thickness linked to better outcomes.
- Notably, 31% of patients returned home without extra rehab, indicating significant challenges in recovery related to early muscle atrophy and strength decline.
Objectives: Diaphragm ultrasound is a novel alternative to esophageal pressure measurements in the evaluation of diaphragm function and activity, but data about its reliability in a pediatric setting are lacking. We aimed to compare the esophageal pressure swing (∆P es , gold standard) with the diaphragmatic thickening fraction (DTF) as a measure of inspiratory effort in sedated children. Additionally, we studied the effect of positive end-expiratory pressure (PEEP) on the end-expiratory thickness of the diaphragm (DT ee ).
View Article and Find Full Text PDFBackground: Flow-controlled ventilation (FCV), a novel mode of mechanical ventilation characterised by constant flow during active expiration, may result in more efficient alveolar gas exchange, better lung recruitment and might be useful in limiting ventilator-induced lung injury. However, data regarding FCV in mechanically ventilated patients with acute lung injury or acute respiratory distress syndrome (ARDS) are scarce.
Objectives: We hypothesised that the use of FCV is feasible and would improve oxygenation in moderate COVID-19 ARDS compared to conventional ventilation.