Brentuximab Vedotin: A Nursing Perspective on Best Practices and Management of Associated Adverse Events.

Background: Brentuximab vedotin (BV) is an antibody-drug conjugate that targets CD30-expressing cells.

Objectives: This article assesses the occurrence and management of the most frequent and clinically relevant BV-associated adverse events (AEs), with a focus on Hodgkin lymphoma and systemic anaplastic large cell lymphoma trials, and shares practical tips that may help decrease occurrence and severity.

Methods: Peer-reviewed literature was surveyed to collect safety data from sponsored clinical trials of BV and to compile associated management guidelines.