Publications by authors named "Gregory K Hanson"
Article Synopsis
- A preclinical model of invasive bladder cancer was created using human mucin 1 (MUC1) transgenic mice to study immunotherapy and chemotherapy effects.
- Mice were treated with a carcinogen (OH-BBN) to induce cancer, and researchers monitored serum cytokine levels and immune responses throughout the study.
- Findings indicated that both MUC1.Tg and wild type mice had a similar cancer incidence and the peptide vaccine led to a positive immune response, confirming the model's utility for future cancer research.
